Mechanisms of Mutagenicity of DNA Adducts Derived from Alkyl and Vinyl Halides

Many small alkyl and vinyl halides are used on a large scale in industrial settings, and most are potentially capable of causing cancer. In general these compounds cause mutations, after activation by various metabolic pathways. In many cases oxidation by cytochrome P450 enzymes results in the forma...

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Veröffentlicht in:	Eisei kagaku 1997/04/30, Vol.43(2), pp.69-82
1. Verfasser:	GUENGERICH, Frederick Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	cytochrome P450 DNA adduct glutathione halogenated hydrocarbon mutagenesis vinyl chloride
Online-Zugang:	Volltext
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