Mechanisms of increased susceptibility of immature and weaned pigs to Escherichia coli heat-stable enterotoxin

Pigs demonstrate an increased sensitivity and susceptibility to Escherichia coli heat-stable enterotoxin (STa) in the 1st wk of life and immediately after weaning. To determine the possible mechanisms for this increased susceptibility, we compared STa binding, guanylate cyclase activation, and photo...

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Veröffentlicht in:	Pediatric research 1991-05, Vol.29 (5), p.424-428
Hauptverfasser:	MEZOFF, A. G, JENSEN, N. J, COHEN, M. B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Suckling Bacterial diseases Bacterial Toxins - metabolism Bacterial Toxins - toxicity Biological and medical sciences Diarrhea - chemically induced Diarrhea - physiopathology Diarrhea - veterinary Disease Susceptibility Enterotoxins - metabolism Enterotoxins - toxicity Enzyme Activation Escherichia coli - pathogenicity Escherichia coli Proteins Guanylate Cyclase - metabolism Infectious diseases Jejunum - drug effects Jejunum - growth & development Jejunum - metabolism Medical sciences Protein Binding Swine - growth & development Swine - physiology Swine Diseases - chemically induced Swine Diseases - physiopathology Weaning
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