Possible involvement of protein kinase C in mediating gastrin-induced response in rat colonic epithelium

We examined the potential role of protein kinase C in signal transduction induced by gastrin's stimulation of rat colonic epithelium. Protein synthesis ([ 35S]methionine incorporation into protein) and enzyme activity (decrease in the cytosolic activity) were measured following epithelial stimu...

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Veröffentlicht in:	Peptides (New York, N.Y. : 1980) N.Y. : 1980), 1991-09, Vol.12 (5), p.925-927
Hauptverfasser:	Yassin, Rihab R., Murthy, S.N.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Analysis of Variance Animals Biological and medical sciences colon Colon - drug effects Colon - enzymology Colon - metabolism Epithelium - drug effects Epithelium - enzymology Epithelium - metabolism Fundamental and applied biological sciences. Psychology Gastrin Gastrins - pharmacology In Vitro Techniques Intestine. Mesentery Isoquinolines - pharmacology Kinetics Male Methionine - metabolism Piperazines - pharmacology PMA Protein Biosynthesis Protein kinase C Protein Kinase C - antagonists & inhibitors Protein Kinase C - metabolism Protein synthesis Rats Rats, Inbred Strains Tetradecanoylphorbol Acetate - pharmacology Vertebrates: digestive system
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