The tetratricopeptide repeat containing Tg737 gene is a liver neoplasia tumor suppressor gene

The Tg737 gene was investigated for gross alterations in a series of rodent/human liver tumors and human tumorigenic cell lines. The Tg737 gene was found to be altered in approximately 40% of the rodent chemically-induced liver tumors, 40% of the human liver tumors, and in liver, kidney and pancreat...

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Veröffentlicht in:	Oncogene 1997-10, Vol.15 (15), p.1797-1803
Hauptverfasser:	ISFORT, R. J, CODY, D. B, WOYCHIK, R. P, DOERSEN, C.-J, RICHARDS, W. G, YODER, B. K, WILKINSON, J. E, KIER, L. D, JIRTLE, R. L, ISENBERG, J. S, KLOUNIG, J. E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Carcinogens Cell culture Cell differentiation Cell Division - genetics Cell physiology Cell proliferation Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Diethylnitrosamine Ectopic expression Fundamental and applied biological sciences. Psychology Gene expression Genes, Tumor Suppressor Hepatocytes Heterozygote Homozygote Humans Kidneys Liver Liver cancer Liver Neoplasms, Experimental - genetics Liver Neoplasms, Experimental - pathology Male Mammalian cells Mice Mice, Inbred C3H Molecular and cellular biology Peptides - chemistry Peptides - genetics Proteins - genetics Stem cell transplantation Stem cells Tumor cell lines Tumor suppressor genes Tumor Suppressor Proteins Tumors
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