A one‐step DGGE scanning method for detection of mutations in the K‐, N‐, and H‐ras oncogenes: Mutations at codons 12, 13 and 61 are rare in B‐cell non‐Hodgkin's lymphoma

Mutations in the N‐, K‐, and H‐ras genes are key events in the process of carcinogenesis of many human cancers and may serve as important targets for therapeutic intervention. We developed a simple diagnostic method that in one step and within 5 hr determines the mutational status of any of the 3 ra...

Ausführliche Beschreibung