Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: a role for FGFR1 in morphogenetic movement through the primitive streak

Fibroblast growth factor (FGF) signaling has been implicated in the patterning of mesoderm and neural lineages during early vertebrate development. In the mouse, FGF receptor-1 (FGFR1) is expressed in an appropriate spatial and temporal manner to be orchestrating these functions. Mouse embryos homoz...

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Veröffentlicht in:	Development (Cambridge) 1997-07, Vol.124 (14), p.2829-2841
Hauptverfasser:	Ciruna, B G, Schwartz, L, Harpal, K, Yamaguchi, T P, Rossant, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Adhesion Cell Movement Chimera Endoderm - cytology Epithelial Cells Gastrula Mesoderm - cytology Mice Mice, Knockout Morphogenesis Mutagenesis, Insertional Nervous System - embryology Receptor Protein-Tyrosine Kinases Receptor, Fibroblast Growth Factor, Type 1 Receptors, Fibroblast Growth Factor - physiology Sequence Deletion
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