Phosphorylation of the β‐subunit of CD11/CD18 integrins by protein kinase C correlates with leukocyte adhesion

Adhesion of activated leukocytes to cells is of critical functional importance. The adhesion is known to be mediated mainly by the CD11/CD18 integrins, also known as leukocytic cell adhesion molecules, or Leu‐CAM. We have now studied the phosphorylation of Leu‐CAM by protein kinase C and the correla...

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Veröffentlicht in:	European journal of immunology 1991-11, Vol.21 (11), p.2857-2862
Hauptverfasser:	Valmu, Leena, Autero, Matti, Siljander, Fia, Patarroyo, Manuel, Gahmberg, Carl G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - metabolism Biological and medical sciences Calcimycin - pharmacology CD18 antigen CD18 Antigens Cell Adhesion Cell interactions, adhesion Fundamental and applied biological sciences. Psychology Humans In Vitro Techniques Integrins - metabolism leucocytes Leukocytes - cytology Leukocytes - metabolism Molecular and cellular biology Phorbol 12,13-Dibutyrate - pharmacology Phosphorylation Phosphoserine - metabolism protein kinase C Protein Kinase C - physiology
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