A tailored approach for endoscopic treatment of small rectal neuroendocrine tumor
Introduction Resection of rectal neuroendocrine tumors (NETs) less than 1 cm in diameter can be performed using various endoscopic techniques. Endoscopic mucosal resection (EMR) traditionally had suboptimal complete resection rate compared to endoscopic submucosal resection with band ligation (ESMR-...
Gespeichert in:
| Veröffentlicht in: | Surgical endoscopy 2014-10, Vol.28 (10), p.2931-2938 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2938 |
|---|---|
| container_issue | 10 |
| container_start_page | 2931 |
| container_title | Surgical endoscopy |
| container_volume | 28 |
| creator | Heo, Jun Jeon, Seong Woo Jung, Min Kyu Kim, Sung Kook Shin, Geun Young Park, Sang Man Ahn, Sun Young Yoon, Won Kyung Kim, Min Kwon, Yong Hwan |
| description | Introduction
Resection of rectal neuroendocrine tumors (NETs) less than 1 cm in diameter can be performed using various endoscopic techniques. Endoscopic mucosal resection (EMR) traditionally had suboptimal complete resection rate compared to endoscopic submucosal resection with band ligation (ESMR-L). However, the previous studies did not consider the characteristics of rectal NETs. The aim of our study is to compare the efficacy of ESMR-L and EMR using tailored approach according to the characteristics of rectal NETs.
Methods
82 rectal NETs in 77 patients treated by ESMR-L (
n
= 48) or EMR (
n
= 34) between September 2007 and October 2012 were retrospectively analyzed. ESMR-L was used for flat-type tumors or tumors with non-lifting sign after submucosal injection. Conventional EMR was used for elevated-type tumors or tumors with well-lifting sign after submucosal injection.
Results
The pathological complete resection rate was higher in the ESMR-L group (45 lesions, 93.8 %) compared with the EMR group (30 lesions, 88.2 %); however, this difference was not significant (
p
= 0.441). Overall complication did not differ significantly between the ESMR-L group and the EMR group (
p
= 0.774). There was one case of a remnant lesion in the ESMR-L group, which was managed by EMR after circumferential pre-cutting (EMR-P), and no recurrence has been detected in either the ESMR-L or EMR group.
Conclusions
ESMR-L and EMR procedures could have a similar excellent complete resection rate, if we select the endoscopic resection technique according to the characteristics of the small rectal NETs. |
| doi_str_mv | 10.1007/s00464-014-3555-1 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1609309467</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1609309467</sourcerecordid><originalsourceid>FETCH-LOGICAL-c442t-3ed2cfe054b7f18802a916b378220d19b733d58373b58f585d31de3ecd96eba13</originalsourceid><addsrcrecordid>eNp1kE1LxDAURYMozjj6A9xIwI2baj6bdDkMfsGACLoOafKqHdpmTNqF_96WGUUEV2-Rk_vuOwidU3JNCVE3iRCRi4xQkXEpZUYP0JwKzjLGqD5Ec1JwkjFViBk6SWlDRryg8hjNmNCSa6Hm6HmJe1s3IYLHdruNwbp3XIWIofMhubCtHe4j2L6Frsehwqm1TYMjuN42uIMhhol0se4A90Mb4ik6qmyT4Gw_F-j17vZl9ZCtn-4fV8t15oRgfcbBM1cBkaJUFdWaMFvQvORKM0Y8LUrFuZeaK15KXUktPaceODhf5FBayhfoapc7lv4YIPWmrZODprEdhCEZmk_nFyJXI3r5B92EIXZju4kiSnJBJoruKBdDShEqs411a-OnocRMvs3Otxl9m8m3mUpc7JOHsgX_8-Nb8AiwHZDGp-4N4q_V_6Z-Aan5ikI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1600753407</pqid></control><display><type>article</type><title>A tailored approach for endoscopic treatment of small rectal neuroendocrine tumor</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Heo, Jun ; Jeon, Seong Woo ; Jung, Min Kyu ; Kim, Sung Kook ; Shin, Geun Young ; Park, Sang Man ; Ahn, Sun Young ; Yoon, Won Kyung ; Kim, Min ; Kwon, Yong Hwan</creator><creatorcontrib>Heo, Jun ; Jeon, Seong Woo ; Jung, Min Kyu ; Kim, Sung Kook ; Shin, Geun Young ; Park, Sang Man ; Ahn, Sun Young ; Yoon, Won Kyung ; Kim, Min ; Kwon, Yong Hwan</creatorcontrib><description>Introduction
Resection of rectal neuroendocrine tumors (NETs) less than 1 cm in diameter can be performed using various endoscopic techniques. Endoscopic mucosal resection (EMR) traditionally had suboptimal complete resection rate compared to endoscopic submucosal resection with band ligation (ESMR-L). However, the previous studies did not consider the characteristics of rectal NETs. The aim of our study is to compare the efficacy of ESMR-L and EMR using tailored approach according to the characteristics of rectal NETs.
Methods
82 rectal NETs in 77 patients treated by ESMR-L (
n
= 48) or EMR (
n
= 34) between September 2007 and October 2012 were retrospectively analyzed. ESMR-L was used for flat-type tumors or tumors with non-lifting sign after submucosal injection. Conventional EMR was used for elevated-type tumors or tumors with well-lifting sign after submucosal injection.
Results
The pathological complete resection rate was higher in the ESMR-L group (45 lesions, 93.8 %) compared with the EMR group (30 lesions, 88.2 %); however, this difference was not significant (
p
= 0.441). Overall complication did not differ significantly between the ESMR-L group and the EMR group (
p
= 0.774). There was one case of a remnant lesion in the ESMR-L group, which was managed by EMR after circumferential pre-cutting (EMR-P), and no recurrence has been detected in either the ESMR-L or EMR group.
Conclusions
ESMR-L and EMR procedures could have a similar excellent complete resection rate, if we select the endoscopic resection technique according to the characteristics of the small rectal NETs.</description><identifier>ISSN: 0930-2794</identifier><identifier>EISSN: 1432-2218</identifier><identifier>DOI: 10.1007/s00464-014-3555-1</identifier><identifier>PMID: 24853847</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Abdominal Surgery ; Adult ; Aged ; Colonoscopy ; Dissection - adverse effects ; Dissection - methods ; Endoscopy ; Endoscopy, Gastrointestinal - adverse effects ; Endoscopy, Gastrointestinal - methods ; Female ; Gastroenterology ; Gynecology ; Hepatology ; Humans ; Internal medicine ; Intestinal Mucosa - pathology ; Intestinal Mucosa - surgery ; Ligation - instrumentation ; Male ; Medicine ; Medicine & Public Health ; Metastasis ; Middle Aged ; Neuroendocrine tumors ; Neuroendocrine Tumors - pathology ; Neuroendocrine Tumors - surgery ; Operative Time ; Physiology ; Postoperative Hemorrhage ; Proctology ; Rectal Neoplasms - pathology ; Rectal Neoplasms - surgery ; Retrospective Studies ; Surgery</subject><ispartof>Surgical endoscopy, 2014-10, Vol.28 (10), p.2931-2938</ispartof><rights>Springer Science+Business Media New York 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c442t-3ed2cfe054b7f18802a916b378220d19b733d58373b58f585d31de3ecd96eba13</citedby><cites>FETCH-LOGICAL-c442t-3ed2cfe054b7f18802a916b378220d19b733d58373b58f585d31de3ecd96eba13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00464-014-3555-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00464-014-3555-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24853847$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Heo, Jun</creatorcontrib><creatorcontrib>Jeon, Seong Woo</creatorcontrib><creatorcontrib>Jung, Min Kyu</creatorcontrib><creatorcontrib>Kim, Sung Kook</creatorcontrib><creatorcontrib>Shin, Geun Young</creatorcontrib><creatorcontrib>Park, Sang Man</creatorcontrib><creatorcontrib>Ahn, Sun Young</creatorcontrib><creatorcontrib>Yoon, Won Kyung</creatorcontrib><creatorcontrib>Kim, Min</creatorcontrib><creatorcontrib>Kwon, Yong Hwan</creatorcontrib><title>A tailored approach for endoscopic treatment of small rectal neuroendocrine tumor</title><title>Surgical endoscopy</title><addtitle>Surg Endosc</addtitle><addtitle>Surg Endosc</addtitle><description>Introduction
Resection of rectal neuroendocrine tumors (NETs) less than 1 cm in diameter can be performed using various endoscopic techniques. Endoscopic mucosal resection (EMR) traditionally had suboptimal complete resection rate compared to endoscopic submucosal resection with band ligation (ESMR-L). However, the previous studies did not consider the characteristics of rectal NETs. The aim of our study is to compare the efficacy of ESMR-L and EMR using tailored approach according to the characteristics of rectal NETs.
Methods
82 rectal NETs in 77 patients treated by ESMR-L (
n
= 48) or EMR (
n
= 34) between September 2007 and October 2012 were retrospectively analyzed. ESMR-L was used for flat-type tumors or tumors with non-lifting sign after submucosal injection. Conventional EMR was used for elevated-type tumors or tumors with well-lifting sign after submucosal injection.
Results
The pathological complete resection rate was higher in the ESMR-L group (45 lesions, 93.8 %) compared with the EMR group (30 lesions, 88.2 %); however, this difference was not significant (
p
= 0.441). Overall complication did not differ significantly between the ESMR-L group and the EMR group (
p
= 0.774). There was one case of a remnant lesion in the ESMR-L group, which was managed by EMR after circumferential pre-cutting (EMR-P), and no recurrence has been detected in either the ESMR-L or EMR group.
Conclusions
ESMR-L and EMR procedures could have a similar excellent complete resection rate, if we select the endoscopic resection technique according to the characteristics of the small rectal NETs.</description><subject>Abdominal Surgery</subject><subject>Adult</subject><subject>Aged</subject><subject>Colonoscopy</subject><subject>Dissection - adverse effects</subject><subject>Dissection - methods</subject><subject>Endoscopy</subject><subject>Endoscopy, Gastrointestinal - adverse effects</subject><subject>Endoscopy, Gastrointestinal - methods</subject><subject>Female</subject><subject>Gastroenterology</subject><subject>Gynecology</subject><subject>Hepatology</subject><subject>Humans</subject><subject>Internal medicine</subject><subject>Intestinal Mucosa - pathology</subject><subject>Intestinal Mucosa - surgery</subject><subject>Ligation - instrumentation</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metastasis</subject><subject>Middle Aged</subject><subject>Neuroendocrine tumors</subject><subject>Neuroendocrine Tumors - pathology</subject><subject>Neuroendocrine Tumors - surgery</subject><subject>Operative Time</subject><subject>Physiology</subject><subject>Postoperative Hemorrhage</subject><subject>Proctology</subject><subject>Rectal Neoplasms - pathology</subject><subject>Rectal Neoplasms - surgery</subject><subject>Retrospective Studies</subject><subject>Surgery</subject><issn>0930-2794</issn><issn>1432-2218</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kE1LxDAURYMozjj6A9xIwI2baj6bdDkMfsGACLoOafKqHdpmTNqF_96WGUUEV2-Rk_vuOwidU3JNCVE3iRCRi4xQkXEpZUYP0JwKzjLGqD5Ec1JwkjFViBk6SWlDRryg8hjNmNCSa6Hm6HmJe1s3IYLHdruNwbp3XIWIofMhubCtHe4j2L6Frsehwqm1TYMjuN42uIMhhol0se4A90Mb4ik6qmyT4Gw_F-j17vZl9ZCtn-4fV8t15oRgfcbBM1cBkaJUFdWaMFvQvORKM0Y8LUrFuZeaK15KXUktPaceODhf5FBayhfoapc7lv4YIPWmrZODprEdhCEZmk_nFyJXI3r5B92EIXZju4kiSnJBJoruKBdDShEqs411a-OnocRMvs3Otxl9m8m3mUpc7JOHsgX_8-Nb8AiwHZDGp-4N4q_V_6Z-Aan5ikI</recordid><startdate>20141001</startdate><enddate>20141001</enddate><creator>Heo, Jun</creator><creator>Jeon, Seong Woo</creator><creator>Jung, Min Kyu</creator><creator>Kim, Sung Kook</creator><creator>Shin, Geun Young</creator><creator>Park, Sang Man</creator><creator>Ahn, Sun Young</creator><creator>Yoon, Won Kyung</creator><creator>Kim, Min</creator><creator>Kwon, Yong Hwan</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20141001</creationdate><title>A tailored approach for endoscopic treatment of small rectal neuroendocrine tumor</title><author>Heo, Jun ; Jeon, Seong Woo ; Jung, Min Kyu ; Kim, Sung Kook ; Shin, Geun Young ; Park, Sang Man ; Ahn, Sun Young ; Yoon, Won Kyung ; Kim, Min ; Kwon, Yong Hwan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c442t-3ed2cfe054b7f18802a916b378220d19b733d58373b58f585d31de3ecd96eba13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Abdominal Surgery</topic><topic>Adult</topic><topic>Aged</topic><topic>Colonoscopy</topic><topic>Dissection - adverse effects</topic><topic>Dissection - methods</topic><topic>Endoscopy</topic><topic>Endoscopy, Gastrointestinal - adverse effects</topic><topic>Endoscopy, Gastrointestinal - methods</topic><topic>Female</topic><topic>Gastroenterology</topic><topic>Gynecology</topic><topic>Hepatology</topic><topic>Humans</topic><topic>Internal medicine</topic><topic>Intestinal Mucosa - pathology</topic><topic>Intestinal Mucosa - surgery</topic><topic>Ligation - instrumentation</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metastasis</topic><topic>Middle Aged</topic><topic>Neuroendocrine tumors</topic><topic>Neuroendocrine Tumors - pathology</topic><topic>Neuroendocrine Tumors - surgery</topic><topic>Operative Time</topic><topic>Physiology</topic><topic>Postoperative Hemorrhage</topic><topic>Proctology</topic><topic>Rectal Neoplasms - pathology</topic><topic>Rectal Neoplasms - surgery</topic><topic>Retrospective Studies</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Heo, Jun</creatorcontrib><creatorcontrib>Jeon, Seong Woo</creatorcontrib><creatorcontrib>Jung, Min Kyu</creatorcontrib><creatorcontrib>Kim, Sung Kook</creatorcontrib><creatorcontrib>Shin, Geun Young</creatorcontrib><creatorcontrib>Park, Sang Man</creatorcontrib><creatorcontrib>Ahn, Sun Young</creatorcontrib><creatorcontrib>Yoon, Won Kyung</creatorcontrib><creatorcontrib>Kim, Min</creatorcontrib><creatorcontrib>Kwon, Yong Hwan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Surgical endoscopy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Heo, Jun</au><au>Jeon, Seong Woo</au><au>Jung, Min Kyu</au><au>Kim, Sung Kook</au><au>Shin, Geun Young</au><au>Park, Sang Man</au><au>Ahn, Sun Young</au><au>Yoon, Won Kyung</au><au>Kim, Min</au><au>Kwon, Yong Hwan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A tailored approach for endoscopic treatment of small rectal neuroendocrine tumor</atitle><jtitle>Surgical endoscopy</jtitle><stitle>Surg Endosc</stitle><addtitle>Surg Endosc</addtitle><date>2014-10-01</date><risdate>2014</risdate><volume>28</volume><issue>10</issue><spage>2931</spage><epage>2938</epage><pages>2931-2938</pages><issn>0930-2794</issn><eissn>1432-2218</eissn><abstract>Introduction
Resection of rectal neuroendocrine tumors (NETs) less than 1 cm in diameter can be performed using various endoscopic techniques. Endoscopic mucosal resection (EMR) traditionally had suboptimal complete resection rate compared to endoscopic submucosal resection with band ligation (ESMR-L). However, the previous studies did not consider the characteristics of rectal NETs. The aim of our study is to compare the efficacy of ESMR-L and EMR using tailored approach according to the characteristics of rectal NETs.
Methods
82 rectal NETs in 77 patients treated by ESMR-L (
n
= 48) or EMR (
n
= 34) between September 2007 and October 2012 were retrospectively analyzed. ESMR-L was used for flat-type tumors or tumors with non-lifting sign after submucosal injection. Conventional EMR was used for elevated-type tumors or tumors with well-lifting sign after submucosal injection.
Results
The pathological complete resection rate was higher in the ESMR-L group (45 lesions, 93.8 %) compared with the EMR group (30 lesions, 88.2 %); however, this difference was not significant (
p
= 0.441). Overall complication did not differ significantly between the ESMR-L group and the EMR group (
p
= 0.774). There was one case of a remnant lesion in the ESMR-L group, which was managed by EMR after circumferential pre-cutting (EMR-P), and no recurrence has been detected in either the ESMR-L or EMR group.
Conclusions
ESMR-L and EMR procedures could have a similar excellent complete resection rate, if we select the endoscopic resection technique according to the characteristics of the small rectal NETs.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>24853847</pmid><doi>10.1007/s00464-014-3555-1</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0930-2794 |
| ispartof | Surgical endoscopy, 2014-10, Vol.28 (10), p.2931-2938 |
| issn | 0930-2794 1432-2218 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1609309467 |
| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Abdominal Surgery Adult Aged Colonoscopy Dissection - adverse effects Dissection - methods Endoscopy Endoscopy, Gastrointestinal - adverse effects Endoscopy, Gastrointestinal - methods Female Gastroenterology Gynecology Hepatology Humans Internal medicine Intestinal Mucosa - pathology Intestinal Mucosa - surgery Ligation - instrumentation Male Medicine Medicine & Public Health Metastasis Middle Aged Neuroendocrine tumors Neuroendocrine Tumors - pathology Neuroendocrine Tumors - surgery Operative Time Physiology Postoperative Hemorrhage Proctology Rectal Neoplasms - pathology Rectal Neoplasms - surgery Retrospective Studies Surgery |
| title | A tailored approach for endoscopic treatment of small rectal neuroendocrine tumor |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T19%3A32%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20tailored%20approach%20for%20endoscopic%20treatment%20of%20small%20rectal%20neuroendocrine%20tumor&rft.jtitle=Surgical%20endoscopy&rft.au=Heo,%20Jun&rft.date=2014-10-01&rft.volume=28&rft.issue=10&rft.spage=2931&rft.epage=2938&rft.pages=2931-2938&rft.issn=0930-2794&rft.eissn=1432-2218&rft_id=info:doi/10.1007/s00464-014-3555-1&rft_dat=%3Cproquest_cross%3E1609309467%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1600753407&rft_id=info:pmid/24853847&rfr_iscdi=true |