Parafibromin, Galectin-3, PGP9.5, Ki67, and Cyclin D1: Using an Immunohistochemical Panel to Aid in the Diagnosis of Parathyroid Cancer

Background Parathyroid cancer is rare. Differentiating parathyroid carcinoma from degenerative changes at histopathology can be difficult and studies investigating the value of single immunohistochemical markers have had variable results. In this study we aimed to investigate whether a panel of immu...

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Veröffentlicht in:	World journal of surgery 2014-11, Vol.38 (11), p.2845-2854
Hauptverfasser:	Truran, Peter P., Johnson, Sarah J., Bliss, Richard D., Lennard, Thomas W. J., Aspinall, Sebastian R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Adenoma - chemistry Adenoma - diagnosis Adult Aged Aged, 80 and over Biomarkers, Tumor - analysis Carcinoma - chemistry Carcinoma - diagnosis Carcinoma - secondary Cardiac Surgery Case-Control Studies Central Lymph Node Dissection Central Lymph Node Metastasis Cyclin D1 - analysis Female Galectin 3 - analysis General Surgery Humans Immunohistochemistry Ki-67 Antigen - analysis Male Medicine Medicine & Public Health Middle Aged Neoplasm Proteins - analysis Parathyroid Adenoma Parathyroid Carcinoma Parathyroid Gland Parathyroid Neoplasms - chemistry Parathyroid Neoplasms - diagnosis Parathyroid Neoplasms - pathology Retrospective Studies Sensitivity and Specificity Surgery Thoracic Surgery Tumor Suppressor Proteins - analysis Ubiquitin Thiolesterase - analysis Vascular Surgery
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