The Effect of Transversus Abdominis Plane Blocks on Postoperative Pain in Laparoscopic Colorectal Surgery: A Prospective, Randomized, Double-Blind Trial
BACKGROUND:Superior early pain control has been suggested with transversus abdominis plane blocks, but evidence-based recommendations for transversus abdominis plane blocks and their effects on patient outcomes are lacking. OBJECTIVE:The aim of this study was to determine whether transversus abdomin...
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| Veröffentlicht in: | Diseases of the colon & rectum 2014-11, Vol.57 (11), p.1290-1297 |
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| creator | Keller, Deborah S Ermlich, Bridget O Schiltz, Nicholas Champagne, Bradley J Reynolds, Harry L Stein, Sharon L Delaney, Conor P |
| description | BACKGROUND:Superior early pain control has been suggested with transversus abdominis plane blocks, but evidence-based recommendations for transversus abdominis plane blocks and their effects on patient outcomes are lacking.
OBJECTIVE:The aim of this study was to determine whether transversus abdominis plane blocks improve early postoperative outcomes in patients undergoing laparoscopic colorectal resection already on an optimized enhanced recovery pathway.
DESIGN:This study is based on a prospective, randomized, double-blind controlled trial.
SETTINGS:The trial was conducted at a tertiary referral center.
PATIENTS:Patients undergoing elective laparoscopic colorectal resection were selected.
INTERVENTIONS(S):Patients were randomly assigned to receive either a transversus abdominis plane block or a placebo placed intraoperatively under laparoscopic guidance. All followed a standardized enhanced recovery pathway. Patient demographics, perioperative procedures, and postoperative outcomes were collected.
MAIN OUTCOME MEASURES:Postoperative pain and nausea/vomiting scores in the postanesthesia care unit and department, opioid use, length of stay, and 30-day readmission rates were measured.
RESULTS:The trial randomly assigned 41 patients to the transversus abdominis plane block group and 38 patients to the control group. Demographic, clinical, and procedural data were not significantly different. In the postanesthesia care unit, the transversus abdominis plane block group had significantly lower pain scores (p < 0.01) and used fewer opioids (p < 0.01) than the control group; postoperative nausea/vomiting scores were comparable (p = 0.99). The transversus abdominis plane group had significantly lower pain scores on postoperative day 1 (p = 0.04) and throughout the study period (p < 0.01). There was no significant difference between groups in postoperative opioid use (p = 0.65) or nausea/vomiting (p = 0.79). The length of stay (median, 2 days experimental, 3 days control; p = 0.50) and readmission rate (7% experimental, 5% control, p = 0.99) was similar across cohorts.
LIMITATIONS:This study was conducted a single center.
CONCLUSIONS:Transversus abdominis plane blocks improved immediate short-term opioid use and pain outcomes. Pain improvement was durable throughout the hospital stay. However, the blocks did not translate into less overall narcotic use, shorter length of stay, or lower readmission rates. |
| doi_str_mv | 10.1097/DCR.0000000000000211 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1609306614</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1609306614</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3017-3aa5fd5b5692c9d08d62b5d55485677af23fc3f4ab548496fa54e31f4195d8b63</originalsourceid><addsrcrecordid>eNpdUdtuEzEUtBCIhsIfIORHHrrF983ylqYtIEUiKuF5ddYXYuqst_Zuq_Il_VwcWkqFZck64zNzPB6E3lJyTElTfzhdXhyTp4tR-gzNqOSkIlzOn6MZIZRVvCbqAL3K-WcpCSP1S3TAJJtL1agZuttsLT5zzuoRR4c3Cfp8bVOeMl50Ju587zNeB-gtPglRX2Yce7yOeYyDTTD6a4vX4Htc9goGSDHrOHiNlzHEVEQh4G9T-mHT7Ue8wOtyPxS00I7wBfT7Ab-sOcKnceqCrU6C7015hIfwGr1wELJ983Aeou_nZ5vl52r19dOX5WJVaU5oXXEA6YzsihumG0PmRrFOGilFMVjX4Bh3mjsBXUFEoxxIYTl1gjbSzDvFD9H7e90hxavJ5rHd-axt2FuOU26pIg0nSlFRWsV9qy42crKuHZLfQbptKWn3mbQlk_b_TArt3cOEqdtZ80j6G8I_3ZsYxvL3l2G6sandWgjj9o8eF5JXjFBBaamqPVTz360Al7M</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1609306614</pqid></control><display><type>article</type><title>The Effect of Transversus Abdominis Plane Blocks on Postoperative Pain in Laparoscopic Colorectal Surgery: A Prospective, Randomized, Double-Blind Trial</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Keller, Deborah S ; Ermlich, Bridget O ; Schiltz, Nicholas ; Champagne, Bradley J ; Reynolds, Harry L ; Stein, Sharon L ; Delaney, Conor P</creator><creatorcontrib>Keller, Deborah S ; Ermlich, Bridget O ; Schiltz, Nicholas ; Champagne, Bradley J ; Reynolds, Harry L ; Stein, Sharon L ; Delaney, Conor P</creatorcontrib><description>BACKGROUND:Superior early pain control has been suggested with transversus abdominis plane blocks, but evidence-based recommendations for transversus abdominis plane blocks and their effects on patient outcomes are lacking.
OBJECTIVE:The aim of this study was to determine whether transversus abdominis plane blocks improve early postoperative outcomes in patients undergoing laparoscopic colorectal resection already on an optimized enhanced recovery pathway.
DESIGN:This study is based on a prospective, randomized, double-blind controlled trial.
SETTINGS:The trial was conducted at a tertiary referral center.
PATIENTS:Patients undergoing elective laparoscopic colorectal resection were selected.
INTERVENTIONS(S):Patients were randomly assigned to receive either a transversus abdominis plane block or a placebo placed intraoperatively under laparoscopic guidance. All followed a standardized enhanced recovery pathway. Patient demographics, perioperative procedures, and postoperative outcomes were collected.
MAIN OUTCOME MEASURES:Postoperative pain and nausea/vomiting scores in the postanesthesia care unit and department, opioid use, length of stay, and 30-day readmission rates were measured.
RESULTS:The trial randomly assigned 41 patients to the transversus abdominis plane block group and 38 patients to the control group. Demographic, clinical, and procedural data were not significantly different. In the postanesthesia care unit, the transversus abdominis plane block group had significantly lower pain scores (p < 0.01) and used fewer opioids (p < 0.01) than the control group; postoperative nausea/vomiting scores were comparable (p = 0.99). The transversus abdominis plane group had significantly lower pain scores on postoperative day 1 (p = 0.04) and throughout the study period (p < 0.01). There was no significant difference between groups in postoperative opioid use (p = 0.65) or nausea/vomiting (p = 0.79). The length of stay (median, 2 days experimental, 3 days control; p = 0.50) and readmission rate (7% experimental, 5% control, p = 0.99) was similar across cohorts.
LIMITATIONS:This study was conducted a single center.
CONCLUSIONS:Transversus abdominis plane blocks improved immediate short-term opioid use and pain outcomes. Pain improvement was durable throughout the hospital stay. However, the blocks did not translate into less overall narcotic use, shorter length of stay, or lower readmission rates.</description><identifier>ISSN: 0012-3706</identifier><identifier>EISSN: 1530-0358</identifier><identifier>DOI: 10.1097/DCR.0000000000000211</identifier><identifier>PMID: 25285696</identifier><language>eng</language><publisher>United States: The American Society of Colon and Rectal Surgeons</publisher><subject>Abdominal Muscles ; Aged ; Analgesics, Opioid - therapeutic use ; Anesthetics, Local - administration & dosage ; Bupivacaine - administration & dosage ; Double-Blind Method ; Female ; Hospitalization ; Humans ; Intestinal Diseases - pathology ; Intestinal Diseases - surgery ; Laparoscopy - adverse effects ; Male ; Middle Aged ; Nerve Block ; Pain, Postoperative - etiology ; Pain, Postoperative - prevention & control ; Postoperative Nausea and Vomiting - etiology ; Postoperative Nausea and Vomiting - prevention & control ; Prospective Studies</subject><ispartof>Diseases of the colon & rectum, 2014-11, Vol.57 (11), p.1290-1297</ispartof><rights>2014 The American Society of Colon and Rectal Surgeons</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3017-3aa5fd5b5692c9d08d62b5d55485677af23fc3f4ab548496fa54e31f4195d8b63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25285696$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Keller, Deborah S</creatorcontrib><creatorcontrib>Ermlich, Bridget O</creatorcontrib><creatorcontrib>Schiltz, Nicholas</creatorcontrib><creatorcontrib>Champagne, Bradley J</creatorcontrib><creatorcontrib>Reynolds, Harry L</creatorcontrib><creatorcontrib>Stein, Sharon L</creatorcontrib><creatorcontrib>Delaney, Conor P</creatorcontrib><title>The Effect of Transversus Abdominis Plane Blocks on Postoperative Pain in Laparoscopic Colorectal Surgery: A Prospective, Randomized, Double-Blind Trial</title><title>Diseases of the colon & rectum</title><addtitle>Dis Colon Rectum</addtitle><description>BACKGROUND:Superior early pain control has been suggested with transversus abdominis plane blocks, but evidence-based recommendations for transversus abdominis plane blocks and their effects on patient outcomes are lacking.
OBJECTIVE:The aim of this study was to determine whether transversus abdominis plane blocks improve early postoperative outcomes in patients undergoing laparoscopic colorectal resection already on an optimized enhanced recovery pathway.
DESIGN:This study is based on a prospective, randomized, double-blind controlled trial.
SETTINGS:The trial was conducted at a tertiary referral center.
PATIENTS:Patients undergoing elective laparoscopic colorectal resection were selected.
INTERVENTIONS(S):Patients were randomly assigned to receive either a transversus abdominis plane block or a placebo placed intraoperatively under laparoscopic guidance. All followed a standardized enhanced recovery pathway. Patient demographics, perioperative procedures, and postoperative outcomes were collected.
MAIN OUTCOME MEASURES:Postoperative pain and nausea/vomiting scores in the postanesthesia care unit and department, opioid use, length of stay, and 30-day readmission rates were measured.
RESULTS:The trial randomly assigned 41 patients to the transversus abdominis plane block group and 38 patients to the control group. Demographic, clinical, and procedural data were not significantly different. In the postanesthesia care unit, the transversus abdominis plane block group had significantly lower pain scores (p < 0.01) and used fewer opioids (p < 0.01) than the control group; postoperative nausea/vomiting scores were comparable (p = 0.99). The transversus abdominis plane group had significantly lower pain scores on postoperative day 1 (p = 0.04) and throughout the study period (p < 0.01). There was no significant difference between groups in postoperative opioid use (p = 0.65) or nausea/vomiting (p = 0.79). The length of stay (median, 2 days experimental, 3 days control; p = 0.50) and readmission rate (7% experimental, 5% control, p = 0.99) was similar across cohorts.
LIMITATIONS:This study was conducted a single center.
CONCLUSIONS:Transversus abdominis plane blocks improved immediate short-term opioid use and pain outcomes. Pain improvement was durable throughout the hospital stay. However, the blocks did not translate into less overall narcotic use, shorter length of stay, or lower readmission rates.</description><subject>Abdominal Muscles</subject><subject>Aged</subject><subject>Analgesics, Opioid - therapeutic use</subject><subject>Anesthetics, Local - administration & dosage</subject><subject>Bupivacaine - administration & dosage</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Intestinal Diseases - pathology</subject><subject>Intestinal Diseases - surgery</subject><subject>Laparoscopy - adverse effects</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Nerve Block</subject><subject>Pain, Postoperative - etiology</subject><subject>Pain, Postoperative - prevention & control</subject><subject>Postoperative Nausea and Vomiting - etiology</subject><subject>Postoperative Nausea and Vomiting - prevention & control</subject><subject>Prospective Studies</subject><issn>0012-3706</issn><issn>1530-0358</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdUdtuEzEUtBCIhsIfIORHHrrF983ylqYtIEUiKuF5ddYXYuqst_Zuq_Il_VwcWkqFZck64zNzPB6E3lJyTElTfzhdXhyTp4tR-gzNqOSkIlzOn6MZIZRVvCbqAL3K-WcpCSP1S3TAJJtL1agZuttsLT5zzuoRR4c3Cfp8bVOeMl50Ju587zNeB-gtPglRX2Yce7yOeYyDTTD6a4vX4Htc9goGSDHrOHiNlzHEVEQh4G9T-mHT7Ue8wOtyPxS00I7wBfT7Ab-sOcKnceqCrU6C7015hIfwGr1wELJ983Aeou_nZ5vl52r19dOX5WJVaU5oXXEA6YzsihumG0PmRrFOGilFMVjX4Bh3mjsBXUFEoxxIYTl1gjbSzDvFD9H7e90hxavJ5rHd-axt2FuOU26pIg0nSlFRWsV9qy42crKuHZLfQbptKWn3mbQlk_b_TArt3cOEqdtZ80j6G8I_3ZsYxvL3l2G6sandWgjj9o8eF5JXjFBBaamqPVTz360Al7M</recordid><startdate>201411</startdate><enddate>201411</enddate><creator>Keller, Deborah S</creator><creator>Ermlich, Bridget O</creator><creator>Schiltz, Nicholas</creator><creator>Champagne, Bradley J</creator><creator>Reynolds, Harry L</creator><creator>Stein, Sharon L</creator><creator>Delaney, Conor P</creator><general>The American Society of Colon and Rectal Surgeons</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201411</creationdate><title>The Effect of Transversus Abdominis Plane Blocks on Postoperative Pain in Laparoscopic Colorectal Surgery: A Prospective, Randomized, Double-Blind Trial</title><author>Keller, Deborah S ; Ermlich, Bridget O ; Schiltz, Nicholas ; Champagne, Bradley J ; Reynolds, Harry L ; Stein, Sharon L ; Delaney, Conor P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3017-3aa5fd5b5692c9d08d62b5d55485677af23fc3f4ab548496fa54e31f4195d8b63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Abdominal Muscles</topic><topic>Aged</topic><topic>Analgesics, Opioid - therapeutic use</topic><topic>Anesthetics, Local - administration & dosage</topic><topic>Bupivacaine - administration & dosage</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Intestinal Diseases - pathology</topic><topic>Intestinal Diseases - surgery</topic><topic>Laparoscopy - adverse effects</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Nerve Block</topic><topic>Pain, Postoperative - etiology</topic><topic>Pain, Postoperative - prevention & control</topic><topic>Postoperative Nausea and Vomiting - etiology</topic><topic>Postoperative Nausea and Vomiting - prevention & control</topic><topic>Prospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Keller, Deborah S</creatorcontrib><creatorcontrib>Ermlich, Bridget O</creatorcontrib><creatorcontrib>Schiltz, Nicholas</creatorcontrib><creatorcontrib>Champagne, Bradley J</creatorcontrib><creatorcontrib>Reynolds, Harry L</creatorcontrib><creatorcontrib>Stein, Sharon L</creatorcontrib><creatorcontrib>Delaney, Conor P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Diseases of the colon & rectum</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Keller, Deborah S</au><au>Ermlich, Bridget O</au><au>Schiltz, Nicholas</au><au>Champagne, Bradley J</au><au>Reynolds, Harry L</au><au>Stein, Sharon L</au><au>Delaney, Conor P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Effect of Transversus Abdominis Plane Blocks on Postoperative Pain in Laparoscopic Colorectal Surgery: A Prospective, Randomized, Double-Blind Trial</atitle><jtitle>Diseases of the colon & rectum</jtitle><addtitle>Dis Colon Rectum</addtitle><date>2014-11</date><risdate>2014</risdate><volume>57</volume><issue>11</issue><spage>1290</spage><epage>1297</epage><pages>1290-1297</pages><issn>0012-3706</issn><eissn>1530-0358</eissn><abstract>BACKGROUND:Superior early pain control has been suggested with transversus abdominis plane blocks, but evidence-based recommendations for transversus abdominis plane blocks and their effects on patient outcomes are lacking.
OBJECTIVE:The aim of this study was to determine whether transversus abdominis plane blocks improve early postoperative outcomes in patients undergoing laparoscopic colorectal resection already on an optimized enhanced recovery pathway.
DESIGN:This study is based on a prospective, randomized, double-blind controlled trial.
SETTINGS:The trial was conducted at a tertiary referral center.
PATIENTS:Patients undergoing elective laparoscopic colorectal resection were selected.
INTERVENTIONS(S):Patients were randomly assigned to receive either a transversus abdominis plane block or a placebo placed intraoperatively under laparoscopic guidance. All followed a standardized enhanced recovery pathway. Patient demographics, perioperative procedures, and postoperative outcomes were collected.
MAIN OUTCOME MEASURES:Postoperative pain and nausea/vomiting scores in the postanesthesia care unit and department, opioid use, length of stay, and 30-day readmission rates were measured.
RESULTS:The trial randomly assigned 41 patients to the transversus abdominis plane block group and 38 patients to the control group. Demographic, clinical, and procedural data were not significantly different. In the postanesthesia care unit, the transversus abdominis plane block group had significantly lower pain scores (p < 0.01) and used fewer opioids (p < 0.01) than the control group; postoperative nausea/vomiting scores were comparable (p = 0.99). The transversus abdominis plane group had significantly lower pain scores on postoperative day 1 (p = 0.04) and throughout the study period (p < 0.01). There was no significant difference between groups in postoperative opioid use (p = 0.65) or nausea/vomiting (p = 0.79). The length of stay (median, 2 days experimental, 3 days control; p = 0.50) and readmission rate (7% experimental, 5% control, p = 0.99) was similar across cohorts.
LIMITATIONS:This study was conducted a single center.
CONCLUSIONS:Transversus abdominis plane blocks improved immediate short-term opioid use and pain outcomes. Pain improvement was durable throughout the hospital stay. However, the blocks did not translate into less overall narcotic use, shorter length of stay, or lower readmission rates.</abstract><cop>United States</cop><pub>The American Society of Colon and Rectal Surgeons</pub><pmid>25285696</pmid><doi>10.1097/DCR.0000000000000211</doi><tpages>8</tpages></addata></record> |
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| identifier | ISSN: 0012-3706 |
| ispartof | Diseases of the colon & rectum, 2014-11, Vol.57 (11), p.1290-1297 |
| issn | 0012-3706 1530-0358 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Abdominal Muscles Aged Analgesics, Opioid - therapeutic use Anesthetics, Local - administration & dosage Bupivacaine - administration & dosage Double-Blind Method Female Hospitalization Humans Intestinal Diseases - pathology Intestinal Diseases - surgery Laparoscopy - adverse effects Male Middle Aged Nerve Block Pain, Postoperative - etiology Pain, Postoperative - prevention & control Postoperative Nausea and Vomiting - etiology Postoperative Nausea and Vomiting - prevention & control Prospective Studies |
| title | The Effect of Transversus Abdominis Plane Blocks on Postoperative Pain in Laparoscopic Colorectal Surgery: A Prospective, Randomized, Double-Blind Trial |
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