Differential blockade of agonist- and depolarization-induced super(45)Ca super(2+) influx in smooth muscle cells

ATP stimulated super(45)Ca super(2+) influx in rat aortic smooth muscle cells in a concentration-dependent manner. ADP and GTP were less effective than ATP in stimulating super(45)Ca super(2+) influx. The data indicate that ATP-stimulated Ca super(2+) influx in rat aortic smooth muscle cells is resi...

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 1989-01, Vol.257 (4), p.C607-C611
Hauptverfasser: Wallnoefer, A, Cauvin, C, Lategan, T W, Rueegg, U T
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container_end_page C611
container_issue 4
container_start_page C607
container_title American Journal of Physiology: Cell Physiology
container_volume 257
creator Wallnoefer, A
Cauvin, C
Lategan, T W
Rueegg, U T
description ATP stimulated super(45)Ca super(2+) influx in rat aortic smooth muscle cells in a concentration-dependent manner. ADP and GTP were less effective than ATP in stimulating super(45)Ca super(2+) influx. The data indicate that ATP-stimulated Ca super(2+) influx in rat aortic smooth muscle cells is resistant to darodipine but is reduced by La super(3+), Cd super(2+), and other inorganic blockers of Ca super(2+) channels. (DBO)
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ispartof American Journal of Physiology: Cell Physiology, 1989-01, Vol.257 (4), p.C607-C611
issn 0363-6143
language eng
recordid cdi_proquest_miscellaneous_16087265
source Alma/SFX Local Collection
subjects ADP
ATP
calcium
comparison
GTP
influx
inhibition
rats
smooth muscle
title Differential blockade of agonist- and depolarization-induced super(45)Ca super(2+) influx in smooth muscle cells
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