Expression of mRNA for gastrin-releasing peptide receptor by human bronchial epithelial cells : Association with prolonged tobacco exposure and responsiveness to bombesin-like peptides

Bombesin-like peptides (BLPs) are important regulators of lung development and may also act as autocrine growth factors in lung tumors. We have previously demonstrated expression of mRNA for the three BLP receptor subtypes (neuromedin B [NMB]) receptor, gastrin-releasing peptide [GRP] receptor, and...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 1997-08, Vol.156 (2), p.358-366
Hauptverfasser:	SIEGFRIED, J. M, DEMICHELE, M. A. A, HUNT, J. D, DAVIS, A. G, VOHRA, K. P, PILEWSKI, J. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Bombesin - drug effects Bombesin - metabolism Bombesin - pharmacology Bronchi - cytology Bronchi - drug effects Bronchi - metabolism Cell Division - drug effects Cells, Cultured Colony-Forming Units Assay Epithelial Cells Epithelium - drug effects Epithelium - metabolism Female Humans Male Medical sciences Middle Aged Nicotiana Plants, Toxic Pneumology Polymerase Chain Reaction - methods Receptors, Bombesin - drug effects Receptors, Bombesin - metabolism RNA, Messenger - drug effects RNA, Messenger - metabolism Smoke - adverse effects Tumors of the respiratory system and mediastinum
Online-Zugang:	Volltext
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