Effect of in vitro treatment of rat hepatocytes with selenium, and/or cadmium on cell viability, glucose output, and cellular glutathione

The effects of cadmium as cadmium acetate and selenium as sodium selenite on glucose output, cell viability, and glutathione levels in rat hepatocytes were evaluated. Isolated hepatocytes (200 mg wet wt cells) derived from naive male Sprague-Dawley rats (210–260 g) were incubated at 37°C, with sodiu...

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Veröffentlicht in:	Toxicology (Amsterdam) 1991, Vol.69 (2), p.111-119
Hauptverfasser:	Bell, R.R., Nonavinakere, V.K., Soliman, M.R.I., Early, J.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cadmium Cadmium - adverse effects Cell Survival - drug effects Cells, Cultured Chemical and industrial products toxicology. Toxic occupational diseases Glucose - metabolism Glucose output Glutathione Glutathione - metabolism Hepatocyte viability Liver - cytology Liver - drug effects Liver - metabolism Male Medical sciences Metals and various inorganic compounds Rats Rats, Inbred Strains Selenium Selenium - adverse effects Toxicology
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