Thiabendazole-induced cytogenetic abnormalities in mouse oocytes

Of the various classes of human genetic disorders, aneuploidy is the most prevalent. Besides its association with maternal age and its predominant origin during maternal meiosis I, little is known about the etiology of aneuploidy. Although various classes of chemicals have been shown to induce aneup...

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Veröffentlicht in:	Environmental and molecular mutagenesis 1997, Vol.29 (4), p.367-371
Hauptverfasser:	Mailhes, John B., Young, Daniel, Aardema, Marilyn J., London, S. N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneuploidy Animals Antinematodal Agents - toxicity Biological and medical sciences Dose-Response Relationship, Drug Drug toxicity and drugs side effects treatment Female Medical sciences Metaphase Mice Mice, Inbred ICR Miscellaneous (drug allergy, mutagens, teratogens...) oocytes Oocytes - drug effects Oocytes - physiology Ovulation Pharmacology. Drug treatments Polyploidy thiabendazole Thiabendazole - toxicity
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