Lymphokine Control of in Vivo Immunoglobulin Isotype Selection

Several specific conclusions can be drawn from these studies: 1. IL-4 is required for the generation of both primary polyclonal and secondary antigen-specific IgE responses in vivo. 2. IL-4 is required to maintain established, ongoing, antigen-specific and polyclonal IgE responses. 3. Most, but not...

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Veröffentlicht in:	Annual review of immunology 1990, Vol.8 (1), p.303-333
Hauptverfasser:	Finkelman, Fred D, Holmes, Joanne, Katona, Ildy M, Urban, Joseph F, Beckmann, M. Patricia, Park, Linda S, Schooley, Kenneth A, Coffman, Robert L, Mosmann, Timothy R, Paul, William E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Humans IgE Immunoglobulin E - immunology Immunoglobulin Isotypes - immunology interferon-α interferon-γ Interferons - physiology interleukin-4 Interleukin-4 - physiology interleukin-5 Interleukin-5 - physiology Lymphokines - physiology
Online-Zugang:	Volltext
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