Activities of cobra venom cytotoxins toward heart and leukemic T-cells depend on localized amino acid differences

Several studies have suggested that along the concave surface of cobra venom cytotoxins, a hydrophobic region flanked by positively charged amino acid side-chains, as well as by tyrosine and/or serine/threonine, allows these toxins to depolarize muscle or cause cytolysis. Comparison of biological ac...

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