Superoxide free radical and intracellular calcium mediate A beta sub(1-42) induced endothelial toxicity

The 39-42 amino acid residue amyloid beta peptide (A beta ), the major protein component in senile plaques and cerebrovascular amyloidosis in the brain in Alzheimer's disease (AD), has been shown to be neurotoxic in vitro. Accumulating data from several areas suggest that cerebrovascular dysfun...

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Veröffentlicht in:	Brain research 1997-07, Vol.762 (1-2), p.144-152
Hauptverfasser:	Suo, Zhiming, Fang, Chunhong, Crawford, F, Mullan, M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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