Methazolamide‐Induced Delirium

A 74‐year‐old man became delirious 2 days after beginning oral therapy with methazolamide. The delirium was manifested by intermittent psychosis, incontinence of bowel and bladder, lethargy, and disorientation. These symptoms continued for 25 days despite many changes in his drug regimen, and comple...

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Veröffentlicht in:Pharmacotherapy 1997-03, Vol.17 (2), p.387-389
Hauptverfasser: Cyr, Monica, Laizure, S. Casey, daCunha, Carl M.
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Laizure, S. Casey
daCunha, Carl M.
description A 74‐year‐old man became delirious 2 days after beginning oral therapy with methazolamide. The delirium was manifested by intermittent psychosis, incontinence of bowel and bladder, lethargy, and disorientation. These symptoms continued for 25 days despite many changes in his drug regimen, and complete laboratory, urologic, and neurologic work‐ups. The symptoms resolved completely within 1 week of discontinuing methazolamide. This is the first case reported of delirium associated with methazolamide not accompanied by a metabolic imbalance.
doi_str_mv 10.1002/j.1875-9114.1997.tb03726.x
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subjects Aged
Biological and medical sciences
Carbonic Anhydrase Inhibitors - adverse effects
Delirium - chemically induced
Delirium - diagnosis
Drug toxicity and drugs side effects treatment
Humans
Male
Medical sciences
Methazolamide - adverse effects
Pharmacology. Drug treatments
Toxicity: nervous system and muscle
title Methazolamide‐Induced Delirium
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