Methazolamide‐Induced Delirium
A 74‐year‐old man became delirious 2 days after beginning oral therapy with methazolamide. The delirium was manifested by intermittent psychosis, incontinence of bowel and bladder, lethargy, and disorientation. These symptoms continued for 25 days despite many changes in his drug regimen, and comple...
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Veröffentlicht in: | Pharmacotherapy 1997-03, Vol.17 (2), p.387-389 |
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creator | Cyr, Monica Laizure, S. Casey daCunha, Carl M. |
description | A 74‐year‐old man became delirious 2 days after beginning oral therapy with methazolamide. The delirium was manifested by intermittent psychosis, incontinence of bowel and bladder, lethargy, and disorientation. These symptoms continued for 25 days despite many changes in his drug regimen, and complete laboratory, urologic, and neurologic work‐ups. The symptoms resolved completely within 1 week of discontinuing methazolamide. This is the first case reported of delirium associated with methazolamide not accompanied by a metabolic imbalance. |
doi_str_mv | 10.1002/j.1875-9114.1997.tb03726.x |
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Casey ; daCunha, Carl M.</creator><creatorcontrib>Cyr, Monica ; Laizure, S. Casey ; daCunha, Carl M.</creatorcontrib><description>A 74‐year‐old man became delirious 2 days after beginning oral therapy with methazolamide. The delirium was manifested by intermittent psychosis, incontinence of bowel and bladder, lethargy, and disorientation. These symptoms continued for 25 days despite many changes in his drug regimen, and complete laboratory, urologic, and neurologic work‐ups. The symptoms resolved completely within 1 week of discontinuing methazolamide. This is the first case reported of delirium associated with methazolamide not accompanied by a metabolic imbalance.</description><identifier>ISSN: 0277-0008</identifier><identifier>EISSN: 1875-9114</identifier><identifier>DOI: 10.1002/j.1875-9114.1997.tb03726.x</identifier><identifier>PMID: 9085335</identifier><identifier>CODEN: PHPYDQ</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Aged ; Biological and medical sciences ; Carbonic Anhydrase Inhibitors - adverse effects ; Delirium - chemically induced ; Delirium - diagnosis ; Drug toxicity and drugs side effects treatment ; Humans ; Male ; Medical sciences ; Methazolamide - adverse effects ; Pharmacology. 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Casey</creatorcontrib><creatorcontrib>daCunha, Carl M.</creatorcontrib><title>Methazolamide‐Induced Delirium</title><title>Pharmacotherapy</title><addtitle>Pharmacotherapy</addtitle><description>A 74‐year‐old man became delirious 2 days after beginning oral therapy with methazolamide. The delirium was manifested by intermittent psychosis, incontinence of bowel and bladder, lethargy, and disorientation. These symptoms continued for 25 days despite many changes in his drug regimen, and complete laboratory, urologic, and neurologic work‐ups. The symptoms resolved completely within 1 week of discontinuing methazolamide. This is the first case reported of delirium associated with methazolamide not accompanied by a metabolic imbalance.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Carbonic Anhydrase Inhibitors - adverse effects</subject><subject>Delirium - chemically induced</subject><subject>Delirium - diagnosis</subject><subject>Drug toxicity and drugs side effects treatment</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Methazolamide - adverse effects</subject><subject>Pharmacology. 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Casey</creator><creator>daCunha, Carl M.</creator><general>Blackwell Publishing Ltd</general><general>Pharmacotherapy</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7U2</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>199703</creationdate><title>Methazolamide‐Induced Delirium</title><author>Cyr, Monica ; Laizure, S. Casey ; daCunha, Carl M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3746-a25baf465d43fc28c5cdeb6d44deea473f38f54132ff49974686a9faa5ebd2613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Carbonic Anhydrase Inhibitors - adverse effects</topic><topic>Delirium - chemically induced</topic><topic>Delirium - diagnosis</topic><topic>Drug toxicity and drugs side effects treatment</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Methazolamide - adverse effects</topic><topic>Pharmacology. Drug treatments</topic><topic>Toxicity: nervous system and muscle</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cyr, Monica</creatorcontrib><creatorcontrib>Laizure, S. Casey</creatorcontrib><creatorcontrib>daCunha, Carl M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Safety Science and Risk</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Pharmacotherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cyr, Monica</au><au>Laizure, S. Casey</au><au>daCunha, Carl M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Methazolamide‐Induced Delirium</atitle><jtitle>Pharmacotherapy</jtitle><addtitle>Pharmacotherapy</addtitle><date>1997-03</date><risdate>1997</risdate><volume>17</volume><issue>2</issue><spage>387</spage><epage>389</epage><pages>387-389</pages><issn>0277-0008</issn><eissn>1875-9114</eissn><coden>PHPYDQ</coden><abstract>A 74‐year‐old man became delirious 2 days after beginning oral therapy with methazolamide. The delirium was manifested by intermittent psychosis, incontinence of bowel and bladder, lethargy, and disorientation. These symptoms continued for 25 days despite many changes in his drug regimen, and complete laboratory, urologic, and neurologic work‐ups. The symptoms resolved completely within 1 week of discontinuing methazolamide. 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source | MEDLINE; Access via Wiley Online Library |
subjects | Aged Biological and medical sciences Carbonic Anhydrase Inhibitors - adverse effects Delirium - chemically induced Delirium - diagnosis Drug toxicity and drugs side effects treatment Humans Male Medical sciences Methazolamide - adverse effects Pharmacology. Drug treatments Toxicity: nervous system and muscle |
title | Methazolamide‐Induced Delirium |
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