Oxidative liver DNA damage in rats treated with pesticide mixtures

Oxidative damage was quantified in the liver of rats by measuring the levels of 8-OH-2-deoxyguanosine (8-OH-2DG) relative to 2-deoxyguanosine in DNA after treating rats for 10 days at a total dose of 1 mg/kg/day with a mixture of the 15 pesticides most commonly found in Italian foods (comprised of d...

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Veröffentlicht in:	Toxicology (Amsterdam) 1997-02, Vol.117 (1), p.55-60
Hauptverfasser:	Lodovici, Maura, Casalini, Chiara, Briani, Carla, Dolara, Piero
Format:	Artikel
Sprache:	eng
Schlagworte:	8-OH-2-deoxyguanosine Administration, Oral Animals Biological and medical sciences DNA Damage - genetics Drug Synergism Liver - drug effects Male Medical sciences Oxidation-Reduction Oxidative DNA damage Pesticides Pesticides - toxicity Pesticides, fertilizers and other agrochemicals toxicology Rats Rats, Wistar Toxicology
Online-Zugang:	Volltext
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