Effect of norepinephrine depletion on audiogenic-like seizures elicited by microinfusion of an excitant amino acid into the inferior colliculus of normal rats

Infusions of an excitant amino acid, N-methyl- d-aspartate (NMDA) into the inferior colliculus (IC) render normal rats susceptible to audiogenic seizures (AGS) and/or spontaneous audiogenic-like seizures without tonic components. The excess excitant amino acid in the IC and the anticonvulsant effect...

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Veröffentlicht in:	Experimental neurology 1991, Vol.112 (2), p.200-205
Hauptverfasser:	Browning, R.A., Wang, C., Faingold, C.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation Animals Biological and medical sciences Brain - drug effects Brain - physiology Hydroxydopamines - pharmacology Inferior Colliculi - drug effects Inferior Colliculi - physiology Inferior Colliculi - physiopathology Infusions, Parenteral Locus Coeruleus - drug effects Locus Coeruleus - physiology Male Medical sciences N-Methylaspartate - administration & dosage N-Methylaspartate - pharmacology Neurology Norepinephrine - physiology Oxidopamine Rats Rats, Inbred Strains Reference Values Seizures - chemically induced Seizures - physiopathology Stereotaxic Techniques
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