ANTINEOPLASTIC ACTIVITY OF CULTURED BLUE-GREEN ALGAE (CYANOPHYTA)

A large-scale screening program was initiated to evaluate laboratory-cultured blue-green algae (cyanobacteria) as a source of novel antineoplastic agents. Approximately 1000 cyanophyte strains from diverse habitats were cultured to provide extracts for testing. The screening program identified the f...

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Veröffentlicht in:	Journal of phycology 1991, Vol.27 (4), p.530-536
Hauptverfasser:	Patterson, Gregory M. L., Baldwin, Cynthia L., Bolis, Christine M., Caplan, Faith R., Karuso, Helen, Larsen, Linda K., Levine, Ira A., Moore, Richard E., Nelson, Carrie S., Tschappat, Kathryn D., Tuang, Grace D., Furusawa, Eiichi, Furusawa, Shinobu, Norton, Ted R., Raybourne, Richard B.
Format:	Artikel
Sprache:	eng
Schlagworte:	anticancer Biological and medical sciences Brackish cyanobacteria Cyanophyta Freshwater General pharmacology Marine Medical sciences microalgae natural products pharmaceutical Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Scytonemataceae Stigonemataceae
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Beschreibung
Zusammenfassung:	A large-scale screening program was initiated to evaluate laboratory-cultured blue-green algae (cyanobacteria) as a source of novel antineoplastic agents. Approximately 1000 cyanophyte strains from diverse habitats were cultured to provide extracts for testing. The screening program identified the families Scytonemataceae and Stigonemataceae as prolific producers of novel cytotoxic compounds. Rates of rediscovery of known compounds were relatively low.
ISSN:	0022-3646 1529-8817
DOI:	10.1111/j.0022-3646.1991.00530.x