Thermally Regulated Translational Control of FRQ Mediates Aspects of Temperature Responses in the Neurospora Circadian Clock

Two forms of FRQ, a central component of the Neurospora circadian clock, arise through alternative in-frame initiation of translation. Either form alone suffices for a functional clock at some temperatures, but both are always necessary for robust rhythmicity. Temperature regulates the ratio of FRQ...

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Veröffentlicht in:	Cell 1997-05, Vol.89 (3), p.477-486
Hauptverfasser:	Liu, Yi, Garceau, Norman Y, Loros, Jennifer J, Dunlap, Jay C
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Clocks - genetics Circadian Rhythm - genetics Codon, Initiator - genetics Fungal Proteins - chemistry Fungal Proteins - genetics Gene Expression Regulation, Fungal - physiology Isomerism Mutagenesis, Site-Directed - physiology Neurospora Neurospora - chemistry Neurospora - genetics Protein Biosynthesis - physiology Temperature
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