Antioxidants As Well As Oxidants Activate C‐fos Via Ras‐Dependent Activation of Extracellular‐Signal‐Regulated Kinase 2 and Elk‐1

Intracellular reactive oxygen intermediate (ROI) levels play an important role in numerous physiological and pathophysiological conditions. Apart from causing oxidative stress and damage, ROI changes differentially activate gene expression. However the proto‐oncogene encoding the AP‐1 transcription...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of biochemistry 1997-02, Vol.244 (1), p.45-52
Hauptverfasser:	Müller, Judith M., Cahill, Michael A., Rupec, Rudolf A., Baeuerle, Patrick A., Nordheim, Alfred
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - pharmacology Calcium-Calmodulin-Dependent Protein Kinases - metabolism c‐fos DNA-Binding Proteins - metabolism Enzyme Activation - drug effects ets-Domain Protein Elk-1 Gene Expression Regulation - drug effects Genes, fos - drug effects Genes, ras - drug effects HeLa Cells Humans Mitogen-Activated Protein Kinase 1 mitogen‐activated protein kinase Nuclear Proteins - metabolism Oxidants - pharmacology Oxidation-Reduction Phosphorylation Protein-Tyrosine Kinases - metabolism Proto-Oncogene Proteins - metabolism Ras redox serum response element Serum Response Factor Signal Transduction Transcription Factors - drug effects Transcription, Genetic - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!