In vitro effects of Celiptium and MR 14504 on mature rat Leydig cell testosterone production

Percoll-purified mature rat Leydig cells have been used to evaluate the testicular toxicity of two highly potent intercalating agents (Celiptium and MR 14505). Testosterone secretion in the absence and in the presence of human chorionic gonadotropin (hCG) was measured to assess Leydig cell function....

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Veröffentlicht in:	Cell biology and toxicology 1997-02, Vol.13 (2), p.83-94
Hauptverfasser:	AL KADRI, H, LANCELOT, J. C, DROSDOWSKY, M. A, AL QUIRBI, A, AL-SAFADI, M, HERNANDEZ, C, ROBBA, M, RAULT, S, CARREAU, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens Animals Biological and medical sciences Cells, Cultured Drug toxicity and drugs side effects treatment Ellipticines - toxicity Humans Intercalating Agents - toxicity Leydig Cells - drug effects Leydig Cells - metabolism Male Medical sciences Men Pharmacology. Drug treatments Rats Rats, Sprague-Dawley Rodents Testosterone Testosterone - biosynthesis Toxicity: urogenital system
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