RFC-1 Gene Expression Regulates Folate Absorption in Mouse Small Intestine

Mediated folate compound transport inward in isolated luminal epithelial cells from mouse small intestine was delineated as pH-dependent and non-pH-dependent components on the basis of their differential sensitivity to the stilbene inhibitor, 4,4â²-diisothiocyanatostilbene-2,2â²-disulfonic acid. p...

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Veröffentlicht in:	The Journal of biological chemistry 1997-04, Vol.272 (17), p.11165-11170
Hauptverfasser:	Chiao, J H, Roy, K, Tolner, B, Yang, C H, Sirotnak, F M
Format:	Artikel
Sprache:	eng
Schlagworte:	4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid - pharmacology Absorption - drug effects Affinity Labels Aminopterin - analogs & derivatives Animals Biological Transport - drug effects Carrier Proteins - biosynthesis Carrier Proteins - genetics Epithelium - drug effects Epithelium - metabolism Folic Acid - analogs & derivatives Gene Expression Intestine, Small - drug effects Intestine, Small - metabolism Membrane Proteins - biosynthesis Membrane Proteins - genetics Membrane Transport Proteins Mice Mice, Inbred C57BL Mice, Inbred DBA RNA, Messenger - isolation & purification Succinimides Tetrahydrofolates - metabolism
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