Combined effects of GDNF, BDNF, and CNTF on motoneuron differentiation in vitro

We have previously shown that glial cell line‐derived neurotrophic factor (GDNF), in addition to promoting the survival of dopaminergic neurons in cultures from embryonic rat ventral mesencephalon, also increases the activity of choline acetyltransferase (ChAT) in the cranial motoneurons present in...

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Veröffentlicht in:	Journal of neuroscience research 1996-04, Vol.44 (2), p.133-141
Hauptverfasser:	Zurn, A.D., Winkel, L., Menoud, A., Djabali, K., Aebischer, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers Brain-Derived Neurotrophic Factor Cell Differentiation - drug effects Cell Survival - drug effects Cells, Cultured Choline O-Acetyltransferase - metabolism Ciliary Neurotrophic Factor Drug Interactions Embryo, Mammalian Eye Proteins - analysis Eye Proteins - biosynthesis Glial Cell Line-Derived Neurotrophic Factor Humans Intermediate Filament Proteins - analysis Intermediate Filament Proteins - biosynthesis Membrane Glycoproteins Mesencephalon - cytology Motor Neuron Disease Motor Neurons - drug effects Motor Neurons - physiology Nerve Growth Factors - pharmacology Nerve Tissue Proteins - pharmacology Neurites - drug effects Neurites - physiology Neurites - ultrastructure neuronal cultures Neuropeptides - analysis Neuropeptides - biosynthesis neurotrophic factors Peripherins Phosphopyruvate Hydratase - analysis Phosphopyruvate Hydratase - metabolism rat Rats Recombinant Proteins - pharmacology
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