Isolation and characterization of the human nucleophosmin/B23 (NPM) gene: Identification of the YY1 binding state at the 5' enhancer region

NPM (nucleophosmin/B23) is a major nucleolar protein which is 20 times more abundant in tumor or proliferating cells than in normal resting cells. Recently, it was found that NPM gene is located at the breakpoints of the t(2:5), t(3:5) and t(5:17) chromosome translocation. To understand the human NP...

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Veröffentlicht in:Nucleic acids research 1997-03, Vol.25 (6), p.1225-1232
Hauptverfasser: Chan, Pui K, Chan, Fung Y, Morris, S W, Xie, Zhong
Format: Artikel
Sprache:eng
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