Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPAR gamma 2 versus PPAR gamma 1 and activation with retinoid X receptor agonists and antagonists

We describe the cloning, characterization, and tissue distribution of the two human peroxisome proliferator activated receptor isoforms hPPAR gamma 2 and hPPAR gamma 1. In cotransfection assays the two isoforms were activated to approximately the same extent by known PPAR gamma activators. Human PPA...

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Veröffentlicht in:The Journal of biological chemistry 1997-03, Vol.272 (12), p.8071-8076
Hauptverfasser: Mukherjee, R, Jow, L, Croston, GE, Paterniti, JR Jr
Format: Artikel
Sprache:eng
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