Sodium bis(hydroxyethyl)dithiocarbamate reduces acute lung tissue damage induced by cadmium in rats

The protective effect of three dithiocarbamates against lung tissue damage induced by a single intratracheal instillation of cadmium chloride was examined in rats. The relative efficacy of these compounds was tested by comparing characteristic features of lung tissue damage: the increase of lung wei...

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Veröffentlicht in:	Fundamental and applied toxicology 1991-05, Vol.16 (4), p.733-741
Hauptverfasser:	Kobrle, Valdemar, Hurych, Josef, Cikrt, Miroslav, Jones, Mark M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cadmium - antagonists & inhibitors Cadmium - metabolism Cadmium Poisoning - pathology Cadmium Poisoning - prevention & control Chemical and industrial products toxicology. Toxic occupational diseases Connective Tissue - drug effects Connective Tissue - metabolism Copper - metabolism Ditiocarb - therapeutic use Lung - metabolism Lung - pathology Lung Diseases - chemically induced Lung Diseases - pathology Lung Diseases - prevention & control Male Medical sciences Metals and various inorganic compounds Organ Size - drug effects Piperidines - therapeutic use Poisoning - drug therapy Rats Rats, Inbred Strains Sorbitol - analogs & derivatives Sorbitol - therapeutic use Thiocarbamates - therapeutic use Toxicology Zinc - metabolism
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