Induction of somatic mutation and recombination by four inhibitors of eukaryotic topoisomerases assayed in the wing spot test of Drosophila melanogaster

Four inhibitors of eukaryotic topoisomerases were investigated for genotoxic effects in the wing spot test of Drosophila melanogaster. As a somatic mutation and recombination test (SMART) this assay assesses mitotic recombination and mutational events of various kinds. We studied camptothecin as a t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Mutagenesis 1996-07, Vol.11 (4), p.315-325
Hauptverfasser:	Frei, Hansjörg, Würgler, Friedrich E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Camptothecin - pharmacology Drosophila melanogaster Drosophila melanogaster - genetics Ellipticines - pharmacology Enzyme Inhibitors - pharmacology Etoposide - pharmacology Female Fundamental and applied biological sciences. Psychology Male Molecular and cellular biology Molecular genetics Mutagenesis. Repair Mutagenicity Tests - methods Mutation Recombination, Genetic - drug effects Teniposide - pharmacology Topoisomerase I Inhibitors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!