Role of oxidative stress in the action of vanadium phosphotyrosine phosphatase inhibitors. Redox independent activation of NF- Kappa B

The role of intracellular oxidative stress in the mechanism of action of phosphotyrosine phosphatase (PTP) inhibitors was studied using three vanadium-based compounds. Sodium orthovanadate (Na sub(3)VO sub(4)), sodium oxodiperoxo(1,10-phenanthroline)vanadate(V) (pV(phen), and bis(maltolato)-oxovanad...

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Veröffentlicht in:The Journal of biological chemistry 1997-04, Vol.272 (17), p.11541-11549
Hauptverfasser: Krejsa, C M, Nadler, S G, Esselstyn, J M, Kavanagh, T J, Ledbetter, JA, Schieven, G L
Format: Artikel
Sprache:eng
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