Effects of intranasal exposure to spores of Stachybotrys atra in mice

The effects of highly toxic and nontoxic spores of Stachybotrys atra were investigated in mice after six intranasal administrations of 1 x 10(5) and 1 x 10(3) spores in phosphate-buffered saline during a 3-week period. Toxic spores contained the trichothecene mycotoxins, satratoxins G and H, as well...

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Veröffentlicht in:	Fundamental and applied toxicology 1997-02, Vol.35 (2), p.182-188
Hauptverfasser:	NIKULIN, M, REIJULA, K, JARVIS, B. B, VEIJALAINEN, P, HINTIKKA, E.-L
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intranasal Animals Antigens, Fungal - immunology Biological and medical sciences Blood Cell Count - drug effects Experimental and animal immunopathology. Animal models Female Immunization Immunoglobulin G - immunology Immunopathology Inflammation - chemically induced Inflammation - pathology Lung - pathology Male Medical sciences Mice Mycotoxins - chemistry Mycotoxins - toxicity Protein Synthesis Inhibitors - chemistry Protein Synthesis Inhibitors - toxicity Spores, Fungal - immunology Stachybotrys - immunology Stachybotrys atra Trichothecenes - chemistry Trichothecenes - toxicity Weight Gain - drug effects
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