Regio-Related Differential Induction of Hepatic Microsomal Heme Oxygenase and Cytochrome P450 by Substituted Imidazole and Pyridine Compounds in Rats

The effects of variously subsituted pyridine and imidazole compounds and some of their chlorinated derivatives on the induction of hepatic microsomal heme oxygenase (HO) and cytochrome P450 (P450) were investigated in rats. 2-Benzylpyridine was able to induce HO to about 4.4-fold the control levels....

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Veröffentlicht in:	Eisei kagaku 1996/12/31, Vol.42(6), pp.468-478
Hauptverfasser:	KOBAYASHI, YASUNA, YAMAMOTO, TOSHINORI, OKUI, EIICHI, KOTANI, EIICHI, YOSHIDA, TAKEMI, KUROIWA, YUKIO
Format:	Artikel
Sprache:	eng
Schlagworte:	cytochrome P450 heme oxygenase pyridine compounds substituted imidazole
Online-Zugang:	Volltext
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