Differential effects of IL-12 receptor blockade with IL-12 p40 homodimer on the induction of CD4 super(+) and CD8 super(+) IFN- gamma -producing cells

The role of IL-12 role in regulating Th1/Th2 balance is attributed in part to the ability of this cytokine to induce IFN gamma production by NK and Th1 cells, which in turn promotes Th1 and inhibits Th2 development. In the present study, the requirement for IL-12 in the development of alloantigen-re...

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Veröffentlicht in:	The Journal of immunology (1950) 1997-01, Vol.158 (2), p.643-648
Hauptverfasser:	Piccotti, J R, Chan, SY, Li, Kewang, Eichwald, E J, Bishop, D K
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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