Influence of Alginate Gel Entrapment and Cryopreservation on Survival and Xenobiotic Metabolism Capacity of Rat Hepatocytes

Rat hepatocytes immobilized in calcium–alginate beads were tested for their ability to survive and functionin vitroby comparison with hepatocyte monolayer cultures before and after cryopreservation. The freeze–thaw protocol previously designed for suspended hepatocytes was used; the freezing medium...

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Veröffentlicht in:	Toxicology and applied pharmacology 1996-12, Vol.141 (2), p.349-356
Hauptverfasser:	Guyomard, Claire, Rialland, Laure, Fremond, Benjamin, Chesne, Christophe, Guillouzo, André
Format:	Artikel
Sprache:	eng
Schlagworte:	Alginates - pharmacology Animals Biological and medical sciences Cell Adhesion Cell Survival Cryopreservation General aspects. Methods Glucuronic Acid Hexuronic Acids Liver - cytology Liver - metabolism Male Medical sciences Rats Rats, Sprague-Dawley Toxicology Xenobiotics - metabolism
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