Protein S Deficiency and HIV Infection
To the Editor: We report two recent cases of patients infected with the human immunodeficiency virus (HIV) presenting with vascular thrombosis and low levels of protein S. To determine whether there is any relation between HIV infection and low plasma levels of protein S, we studied the prevalence o...
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| Veröffentlicht in: | The New England journal of medicine 1991-04, Vol.324 (17), p.1220-1220 |
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| container_end_page | 1220 |
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| container_issue | 17 |
| container_start_page | 1220 |
| container_title | The New England journal of medicine |
| container_volume | 324 |
| creator | Lafeuillade, A Alessi, M C Poizot-Martin, I Dhiver, C Quilichini, R Aubert, L Gastaut, J A Juhan-Vague, I |
| description | To the Editor:
We report two recent cases of patients infected with the human immunodeficiency virus (HIV) presenting with vascular thrombosis and low levels of protein S. To determine whether there is any relation between HIV infection and low plasma levels of protein S, we studied the prevalence of protein S deficiency in 71 HIV-infected persons seen for routine laboratory tests over a period of one month.
The first patient was a 29-year-old homosexual man who was HIV-positive (Centers for Disease Control [CDC] Group IV-C-2) and had been admitted to the hospital for edema of the legs due to thrombosis . . . |
| doi_str_mv | 10.1056/NEJM199104253241717 |
| format | Article |
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We report two recent cases of patients infected with the human immunodeficiency virus (HIV) presenting with vascular thrombosis and low levels of protein S. To determine whether there is any relation between HIV infection and low plasma levels of protein S, we studied the prevalence of protein S deficiency in 71 HIV-infected persons seen for routine laboratory tests over a period of one month.
The first patient was a 29-year-old homosexual man who was HIV-positive (Centers for Disease Control [CDC] Group IV-C-2) and had been admitted to the hospital for edema of the legs due to thrombosis . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199104253241717</identifier><identifier>PMID: 1826342</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Adult ; Glycoproteins - deficiency ; HIV Infections - blood ; Humans ; Male ; Middle Aged ; Protein S</subject><ispartof>The New England journal of medicine, 1991-04, Vol.324 (17), p.1220-1220</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c336t-750f1d1c5872fb3b471545142ed14e6eced5711d9ec44ab9c2afea7a3fd43f793</citedby><cites>FETCH-LOGICAL-c336t-750f1d1c5872fb3b471545142ed14e6eced5711d9ec44ab9c2afea7a3fd43f793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199104253241717$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJM199104253241717$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,780,784,2759,2760,26103,27924,27925,52382,54064,64387</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1826342$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lafeuillade, A</creatorcontrib><creatorcontrib>Alessi, M C</creatorcontrib><creatorcontrib>Poizot-Martin, I</creatorcontrib><creatorcontrib>Dhiver, C</creatorcontrib><creatorcontrib>Quilichini, R</creatorcontrib><creatorcontrib>Aubert, L</creatorcontrib><creatorcontrib>Gastaut, J A</creatorcontrib><creatorcontrib>Juhan-Vague, I</creatorcontrib><title>Protein S Deficiency and HIV Infection</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
We report two recent cases of patients infected with the human immunodeficiency virus (HIV) presenting with vascular thrombosis and low levels of protein S. To determine whether there is any relation between HIV infection and low plasma levels of protein S, we studied the prevalence of protein S deficiency in 71 HIV-infected persons seen for routine laboratory tests over a period of one month.
The first patient was a 29-year-old homosexual man who was HIV-positive (Centers for Disease Control [CDC] Group IV-C-2) and had been admitted to the hospital for edema of the legs due to thrombosis . . .</description><subject>Adult</subject><subject>Glycoproteins - deficiency</subject><subject>HIV Infections - blood</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Protein S</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLw0AUhQdRaq3-AhGyciPRufPIZJZSq63UB_jYDpOZO5DSJDWTLvrvjaTgRrybszjnfFwOIedAr4HK7OZ59vgEWgMVTHImQIE6IGOQnKdC0OyQjClleSqU5sfkJMYV7Q-EHpER5Czjgo3J5WvbdFjWyVtyh6F0JdZul9jaJ_PFZ7KoA7qubOpTchTsOuLZXifk4372Pp2ny5eHxfR2mTrOsy5Vkgbw4GSuWCh4IRRIIUEw9CAwQ4deKgCv0QlhC-2YDWiV5cELHvo_J-Ry4G7a5muLsTNVGR2u17bGZhsNyFyrTPE-yIega5sYWwxm05aVbXcGqPlZx_yxTt-62OO3RYX-tzPM0ftXg19V0dS4qv6lfQOO5mnE</recordid><startdate>19910425</startdate><enddate>19910425</enddate><creator>Lafeuillade, A</creator><creator>Alessi, M C</creator><creator>Poizot-Martin, I</creator><creator>Dhiver, C</creator><creator>Quilichini, R</creator><creator>Aubert, L</creator><creator>Gastaut, J A</creator><creator>Juhan-Vague, I</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope></search><sort><creationdate>19910425</creationdate><title>Protein S Deficiency and HIV Infection</title><author>Lafeuillade, A ; Alessi, M C ; Poizot-Martin, I ; Dhiver, C ; Quilichini, R ; Aubert, L ; Gastaut, J A ; Juhan-Vague, I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c336t-750f1d1c5872fb3b471545142ed14e6eced5711d9ec44ab9c2afea7a3fd43f793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Adult</topic><topic>Glycoproteins - deficiency</topic><topic>HIV Infections - blood</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Protein S</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lafeuillade, A</creatorcontrib><creatorcontrib>Alessi, M C</creatorcontrib><creatorcontrib>Poizot-Martin, I</creatorcontrib><creatorcontrib>Dhiver, C</creatorcontrib><creatorcontrib>Quilichini, R</creatorcontrib><creatorcontrib>Aubert, L</creatorcontrib><creatorcontrib>Gastaut, J A</creatorcontrib><creatorcontrib>Juhan-Vague, I</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lafeuillade, A</au><au>Alessi, M C</au><au>Poizot-Martin, I</au><au>Dhiver, C</au><au>Quilichini, R</au><au>Aubert, L</au><au>Gastaut, J A</au><au>Juhan-Vague, I</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Protein S Deficiency and HIV Infection</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>1991-04-25</date><risdate>1991</risdate><volume>324</volume><issue>17</issue><spage>1220</spage><epage>1220</epage><pages>1220-1220</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>To the Editor:
We report two recent cases of patients infected with the human immunodeficiency virus (HIV) presenting with vascular thrombosis and low levels of protein S. To determine whether there is any relation between HIV infection and low plasma levels of protein S, we studied the prevalence of protein S deficiency in 71 HIV-infected persons seen for routine laboratory tests over a period of one month.
The first patient was a 29-year-old homosexual man who was HIV-positive (Centers for Disease Control [CDC] Group IV-C-2) and had been admitted to the hospital for edema of the legs due to thrombosis . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>1826342</pmid><doi>10.1056/NEJM199104253241717</doi><tpages>1</tpages></addata></record> |
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| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 1991-04, Vol.324 (17), p.1220-1220 |
| issn | 0028-4793 1533-4406 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_15897673 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
| subjects | Adult Glycoproteins - deficiency HIV Infections - blood Humans Male Middle Aged Protein S |
| title | Protein S Deficiency and HIV Infection |
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