Effect of acetone administration on renal, pulmonary and hepatic monooxygenase activities in hamster

Administration of acetone in drinking water to Syrian Golden hamster for 9–10 days altered microsomal P-450 dependent monooxygenase activities in the liver and the kidney but not in the lung. While hepatic microsomal NADPH-cytochrome c reductase was unaffected, cytochrome b 5 and P-450 content incre...

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Veröffentlicht in:	Toxicology (Amsterdam) 1990-11, Vol.64 (2), p.141-153
Hauptverfasser:	Menicagli, S., Puccini, P., Longo, V., Gervasi, P.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetone - pharmacology Administration, Oral Animals Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Cricetinae Cytochrome P-450 Enzyme System - metabolism Dimethyl Sulfoxide - metabolism Electrophoresis, Polyacrylamide Gel Enzyme Activation - drug effects Kidney - drug effects Kidney - enzymology Liver - drug effects Liver - enzymology Lung - drug effects Lung - enzymology Male Medical sciences Mesocricetus Microsomes - drug effects Microsomes - enzymology Oxygenases - metabolism Solvents Toxicology
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