Toxicity, immunogenicity, and tumor radioimmunodetecting ability of two human monoclonal antibodies in patients with metastatic colorectal carcinoma

Two human immunoglobulin M (IgM) monoclonal antibodies (MoAbs), 16.88 and 28A32, which react with cytoplasmic (28A32 and 16.88) or cell surface (28A32) determinants on human colon carcinoma cells, were administered intravenously to 26 patients with metastatic colorectal carcinoma to determine if the...

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Veröffentlicht in:	Journal of clinical oncology 1990-03, Vol.8 (3), p.476-490
Hauptverfasser:	R G Steis, J A Carrasquillo, R McCabe, M A Bookman, J C Reynolds, S M Larson, J W Smith, 2nd, J W Clark, V Dailey, S Del Vecchio
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - pharmacology Antigens, Neoplasm - analysis Colorectal Neoplasms - immunology Epitopes - analysis Female Humans Iodine Radioisotopes Male Middle Aged Neoplasm Metastasis - immunology Radioimmunoassay
Online-Zugang:	Volltext
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