Pediatric Procedural Sedation With Propofol Using a Higher Initial Bolus Dose
OBJECTIVESWe sought to describe the doses of propofol used for sedation in our pediatric emergency department, along with the range of procedures performed under propofol sedation. We also planned to describe clinically important physiologic changes seen and physician satisfaction with propofol at t...
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| Veröffentlicht in: | Pediatric emergency care 2014-10, Vol.30 (10), p.689-693 |
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| container_title | Pediatric emergency care |
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| creator | Young, Timothy P Lim, Jennifer J Kim, Tommy Y Thorp, Andrea W Brown, Lance |
| description | OBJECTIVESWe sought to describe the doses of propofol used for sedation in our pediatric emergency department, along with the range of procedures performed under propofol sedation. We also planned to describe clinically important physiologic changes seen and physician satisfaction with propofol at the doses observed.
METHODSThis was a prospective observational case series. Physicians completed a data collection form after the propofol sedation. The physicians were asked to report physiologic changes that occurred during sedation and rate their satisfaction with propofol as a sedation agent on a 100-mm visual analog scale.
RESULTSEight hundred eighty-six sedation events were reported. The median initial dose of propofol given was 2.0 mg/kg and the median total dose was 3.6 mg/kg. Propofol was used for a wide range of procedures. The most common physiologic change was desaturation/hypoxia (desaturation to |
| doi_str_mv | 10.1097/PEC.0000000000000229 |
| format | Article |
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METHODSThis was a prospective observational case series. Physicians completed a data collection form after the propofol sedation. The physicians were asked to report physiologic changes that occurred during sedation and rate their satisfaction with propofol as a sedation agent on a 100-mm visual analog scale.
RESULTSEight hundred eighty-six sedation events were reported. The median initial dose of propofol given was 2.0 mg/kg and the median total dose was 3.6 mg/kg. Propofol was used for a wide range of procedures. The most common physiologic change was desaturation/hypoxia (desaturation to <90% in 7.2%). No deaths, unplanned intubations, or surgical airway placements were reported. Treating physicians reported a median satisfaction score of 97 mm.
CONCLUSIONSA 2-mg/kg initial bolus dose of propofol for pediatric sedation was well tolerated and useful for a wide range of procedures. Physicians should expect to find a high level of satisfaction with this dose.</description><identifier>ISSN: 0749-5161</identifier><identifier>EISSN: 1535-1815</identifier><identifier>DOI: 10.1097/PEC.0000000000000229</identifier><identifier>PMID: 25272069</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins, Inc</publisher><subject>Adolescent ; Child ; Child, Preschool ; Deep Sedation - methods ; Female ; Humans ; Hypnotics and Sedatives - administration & dosage ; Infant ; Male ; Propofol - administration & dosage ; Prospective Studies ; Young Adult</subject><ispartof>Pediatric emergency care, 2014-10, Vol.30 (10), p.689-693</ispartof><rights>2014 Lippincott Williams & Wilkins, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4269-3b1bac359e4a00e9133494017b9976bbd79652a893f92cb6d86c38b17baf84ca3</citedby><cites>FETCH-LOGICAL-c4269-3b1bac359e4a00e9133494017b9976bbd79652a893f92cb6d86c38b17baf84ca3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25272069$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Young, Timothy P</creatorcontrib><creatorcontrib>Lim, Jennifer J</creatorcontrib><creatorcontrib>Kim, Tommy Y</creatorcontrib><creatorcontrib>Thorp, Andrea W</creatorcontrib><creatorcontrib>Brown, Lance</creatorcontrib><title>Pediatric Procedural Sedation With Propofol Using a Higher Initial Bolus Dose</title><title>Pediatric emergency care</title><addtitle>Pediatr Emerg Care</addtitle><description>OBJECTIVESWe sought to describe the doses of propofol used for sedation in our pediatric emergency department, along with the range of procedures performed under propofol sedation. We also planned to describe clinically important physiologic changes seen and physician satisfaction with propofol at the doses observed.
METHODSThis was a prospective observational case series. Physicians completed a data collection form after the propofol sedation. The physicians were asked to report physiologic changes that occurred during sedation and rate their satisfaction with propofol as a sedation agent on a 100-mm visual analog scale.
RESULTSEight hundred eighty-six sedation events were reported. The median initial dose of propofol given was 2.0 mg/kg and the median total dose was 3.6 mg/kg. Propofol was used for a wide range of procedures. The most common physiologic change was desaturation/hypoxia (desaturation to <90% in 7.2%). No deaths, unplanned intubations, or surgical airway placements were reported. Treating physicians reported a median satisfaction score of 97 mm.
CONCLUSIONSA 2-mg/kg initial bolus dose of propofol for pediatric sedation was well tolerated and useful for a wide range of procedures. Physicians should expect to find a high level of satisfaction with this dose.</description><subject>Adolescent</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Deep Sedation - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Hypnotics and Sedatives - administration & dosage</subject><subject>Infant</subject><subject>Male</subject><subject>Propofol - administration & dosage</subject><subject>Prospective Studies</subject><subject>Young Adult</subject><issn>0749-5161</issn><issn>1535-1815</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1KAzEURoMotlbfQCRLN1PzM8lMllqrFSoWtLgMmUymE02bmsxQfHuntIq48G7u4jv3u3AAOMdoiJHIrmbj0RD9HkLEAehjRlmCc8wOQR9lqUgY5rgHTmJ8Q6gLKT0GPcJIRhAXffA4M6VVTbAazoLXpmyDcvDZlKqxfgVfbVNvg7WvvIPzaFcLqODELmoT4MPKNrajb7xrI7z10ZyCo0q5aM72ewDmd-OX0SSZPt0_jK6niU4JFwktcKE0ZcKkCiEjMKWpSBHOCiEyXhRlJjgjKhe0EkQXvMy5pnnR5arKU63oAFzuetfBf7QmNnJpozbOqZXxbZSY5Rx3fUh0aLpDdfAxBlPJdbBLFT4lRnIrUnYi5V-R3dnF_kNbLE35c_RtrgPyHbDxrjEhvrt2Y4KsjXJN_X_3F8vqfbc</recordid><startdate>201410</startdate><enddate>201410</enddate><creator>Young, Timothy P</creator><creator>Lim, Jennifer J</creator><creator>Kim, Tommy Y</creator><creator>Thorp, Andrea W</creator><creator>Brown, Lance</creator><general>Lippincott Williams & Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201410</creationdate><title>Pediatric Procedural Sedation With Propofol Using a Higher Initial Bolus Dose</title><author>Young, Timothy P ; Lim, Jennifer J ; Kim, Tommy Y ; Thorp, Andrea W ; Brown, Lance</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4269-3b1bac359e4a00e9133494017b9976bbd79652a893f92cb6d86c38b17baf84ca3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adolescent</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Deep Sedation - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Hypnotics and Sedatives - administration & dosage</topic><topic>Infant</topic><topic>Male</topic><topic>Propofol - administration & dosage</topic><topic>Prospective Studies</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Young, Timothy P</creatorcontrib><creatorcontrib>Lim, Jennifer J</creatorcontrib><creatorcontrib>Kim, Tommy Y</creatorcontrib><creatorcontrib>Thorp, Andrea W</creatorcontrib><creatorcontrib>Brown, Lance</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric emergency care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Young, Timothy P</au><au>Lim, Jennifer J</au><au>Kim, Tommy Y</au><au>Thorp, Andrea W</au><au>Brown, Lance</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pediatric Procedural Sedation With Propofol Using a Higher Initial Bolus Dose</atitle><jtitle>Pediatric emergency care</jtitle><addtitle>Pediatr Emerg Care</addtitle><date>2014-10</date><risdate>2014</risdate><volume>30</volume><issue>10</issue><spage>689</spage><epage>693</epage><pages>689-693</pages><issn>0749-5161</issn><eissn>1535-1815</eissn><abstract>OBJECTIVESWe sought to describe the doses of propofol used for sedation in our pediatric emergency department, along with the range of procedures performed under propofol sedation. We also planned to describe clinically important physiologic changes seen and physician satisfaction with propofol at the doses observed.
METHODSThis was a prospective observational case series. Physicians completed a data collection form after the propofol sedation. The physicians were asked to report physiologic changes that occurred during sedation and rate their satisfaction with propofol as a sedation agent on a 100-mm visual analog scale.
RESULTSEight hundred eighty-six sedation events were reported. The median initial dose of propofol given was 2.0 mg/kg and the median total dose was 3.6 mg/kg. Propofol was used for a wide range of procedures. The most common physiologic change was desaturation/hypoxia (desaturation to <90% in 7.2%). No deaths, unplanned intubations, or surgical airway placements were reported. Treating physicians reported a median satisfaction score of 97 mm.
CONCLUSIONSA 2-mg/kg initial bolus dose of propofol for pediatric sedation was well tolerated and useful for a wide range of procedures. Physicians should expect to find a high level of satisfaction with this dose.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>25272069</pmid><doi>10.1097/PEC.0000000000000229</doi><tpages>5</tpages></addata></record> |
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| ispartof | Pediatric emergency care, 2014-10, Vol.30 (10), p.689-693 |
| issn | 0749-5161 1535-1815 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adolescent Child Child, Preschool Deep Sedation - methods Female Humans Hypnotics and Sedatives - administration & dosage Infant Male Propofol - administration & dosage Prospective Studies Young Adult |
| title | Pediatric Procedural Sedation With Propofol Using a Higher Initial Bolus Dose |
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