Copper-Catalyzed One-Pot Synthesis of N‑Aryl Oxazolidinones from Amino Alcohol Carbamates

An efficient sequential intramolecular cyclization of amino alcohol carbamates followed by Cu-catalyzed cross-coupling with aryl iodides under mild conditions has been developed. The reaction occurred in good yields and tolerated aryl iodides containing functionalities such as nitriles, ketones, eth...

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Veröffentlicht in:	Organic letters 2014-10, Vol.16 (19), p.5020-5023
Hauptverfasser:	Mahy, William, Plucinski, Pawel K, Frost, Christopher G
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Alcohols - chemistry Carbamates - chemistry Catalysis Copper - chemistry Cyclization Hydrocarbons, Iodinated - chemistry Molecular Structure Oxazolidinones - chemical synthesis Oxazolidinones - chemistry
Online-Zugang:	Volltext
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