Transposon Tc1-Derived, Sequence-Tagged Sites in Caenorhabditis elegans as Markers for Gene Mapping

We present an approach to map large numbers of Tc1 transposon insertions in the genome of Caenorhabditis elegans. Strains have been described that contain up to 500 polymorphic Tc1 insertions. From these we have cloned and shotgun sequenced over 2000 Tc1 flanks, resulting in an estimated set of 400...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1996-12, Vol.93 (25), p.14680-14685
Hauptverfasser:	Korswagen, Hendrik C., Durbin, Richard M., Smits, Miriam T., Ronald H. A. Plasterk
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Biological Sciences Biomarkers Caenorhabditis elegans Caenorhabditis elegans - genetics Chromosome Mapping DNA DNA Transposable Elements Genetic mapping Genetic mutation Genetics Genome Genomes Genomics Mutation Polymerase chain reaction Sequence tagged sites Sequencing Worms
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