Stable lead isotope profiles in smelter and general urban communities: a comparison of environmental and blood measures

Stable lead isotope profiles in smelter and general urban communities: a comparison of environmental and blood measures

High-precision lead isotope ratios and lead concentrations have been compared statistically and graphically in women of child-bearing age (n = 77) from two smelter communities and one general urban community to evaluate the relative contributions to blood lead of tissue lead stores and lead from the...

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Veröffentlicht in:Environmental geochemistry and health 1996-12, Vol.18 (4), p.147-163
Hauptverfasser: Gulson, B L, Pisaniello, D, McMichael, A J, Mizon, K J, Korsch, M J, Luke, C, Ashbolt, R, Pederson, D G, Vimpani, G, Mahaffey, K R
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container_end_page 163
container_issue 4
container_start_page 147
container_title Environmental geochemistry and health
container_volume 18
creator Gulson, B L
Pisaniello, D
McMichael, A J
Mizon, K J
Korsch, M J
Luke, C
Ashbolt, R
Pederson, D G
Vimpani, G
Mahaffey, K R
description High-precision lead isotope ratios and lead concentrations have been compared statistically and graphically in women of child-bearing age (n = 77) from two smelter communities and one general urban community to evaluate the relative contributions to blood lead of tissue lead stores and lead from the contemporaneous environment (soil, floor dust, indoor airborne dust, water, food). Blood lead (PbB) contents were generally low (e.g.
doi_str_mv 10.1007/BF01771238
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Blood lead (PbB) contents were generally low (e.g. &lt;10 μg dL(-1)). Statistically significant isotopic differences in blood and environmental samples were observed between the three cities although isotopic differences in blood for individual subjects living in close proximity (∼200 m radius) was as large as the differences within a city. No single environmental measure dominated the biological isotope profile and in many cases the low levels of blood lead meant that their isotopic profiles could be easily perturbed by relatively small changes of environmental exposure. Apportioning of sources using lead isotopes is possibly not feasible, nor cost effective, when blood lead levels are &lt;5 μg dL(-1). Interpretations based on statistical analyses of city-wide data do not give the same conclusions as when the houses are considered individually. Aggregating data from multiple subjects in a study such as this obscures potentially useful information. 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title Stable lead isotope profiles in smelter and general urban communities: a comparison of environmental and blood measures
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