Non-replicating recombinant vaccinia virus encoding murine B-7 molecules elicits effective costimulation of naive CD4 super(+) splenocytes in vitro

Using a series of new insertion/expression vectors, we constructed a set of recombinant vaccinia viruses (recVV) encoding the murine T cell costimulatory molecules mB7-1 or mB7-2, or both together in the same construct. On infection with replication incompetent and non-cytopathic recVV, several tumo...

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Veröffentlicht in:	Journal of general virology 1996-12, Vol.77 (12), p.3121-3125
Hauptverfasser:	Oertli, D, Marti, W R, Norton, JA, Tsung, K
Format:	Artikel
Sprache:	eng
Schlagworte:	vaccinia virus
Online-Zugang:	Volltext
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