Selective cytolysis by a protein toxin as a consequence of direct interaction with the lymphocyte plasma membrane

Two lines of evidence support the concept that cardiotoxin from Naja naja siamensis interacts directly with the plama membrane to produce selective cytolysis of lymphocytes. Toxin adsorbed to the wells of microtiter plates retained the ability to lyse murine T-lymphocytes, but lost the ability to de...

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Veröffentlicht in:Toxicology and applied pharmacology 1990-06, Vol.104 (2), p.290-300
Hauptverfasser: Hinman, Channing L., Jiang, Xiao Ling, Tang, Hai-Ping
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Sprache:eng
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