Cellular expression of ionotropic glutamate receptor subunits on specific striatal neuron types and its implication for striatal vulnerability in glutamate receptor-mediated excitotoxicity

Glutamate receptors are composed of subtype-specific subunits. Variation in the precise subunit composition of a receptor may result in significant functional differences. Thus, a precise knowledge of subunit composition on striatal neurons is a prerequisite for understanding the selective vulnerabi...

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Veröffentlicht in:	Neuroscience 1996-08, Vol.73 (3), p.715-731
Hauptverfasser:	Chen, Q., Veenman, C.L., Reiner, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	AMPA Animals ChAT choline acetyltransferase Corpus Striatum - metabolism Cy-5 cyanine-5 dichlorotriazinylamino fluorescein DTAF ENK enkaphalin entopeduncular nucleus excitatory amino acids FluoroGold globus pallidus Huntington's disease Immunohistochemistry Interneurons - metabolism kainate kainic acid Male N-methyl- d-aspartate neurodegenerative disease Neurotoxins - toxicity nitric oxide synthase NMDA NOS PARV parvalbumin phosphate buffer quinolinic acid Rats Rats, Sprague-Dawley Receptors, Glutamate - classification Receptors, Glutamate - metabolism SN pars compacta SN pars reticulata SNc SNr striatum substance P substantia nigra tetramethyl rhodamine TRITC α-amino-3-hydroxy-5-methyl-4-isoxazole propionate
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