Regulation of hexose transport in aortic endothelial cells by vascular permeability factor and tumor necrosis factor-alpha, but not by insulin

Vascular permeability factor (VPF) is mitogenic for bovine aortic endothelial (BAE) cells, whereas tumor necrosis factor (TNF) is cytostatic and was found to completely block the mitogenic response to VPF. In contrast to the apparently antagonistic mitogenic effects that these two factors elicit, ch...

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Veröffentlicht in:	The Journal of biological chemistry 1990-10, Vol.265 (30), p.18051-18054
Hauptverfasser:	Pekala, P, Marlow, M, Heuvelman, D, Connolly, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta Biological and medical sciences Biological Transport - drug effects Blotting, Northern Cattle Cell Division - drug effects Cell Line Cell physiology Deoxyglucose - metabolism endothelial cells Endothelial Growth Factors - pharmacology Endothelium, Vascular - metabolism Fundamental and applied biological sciences. Psychology Gene Expression glucose Hexoses - metabolism In Vitro Techniques insulin Insulin - pharmacology Lymphokines - pharmacology Molecular and cellular biology Monosaccharide Transport Proteins - genetics Responses to growth factors, tumor promotors, other factors tumor necrosis factor- alpha Tumor Necrosis Factor-alpha - pharmacology Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factors vascular permeability factor
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