The inter-locus recombinant HLA-B super()4601 has high selectivity in peptide binding and functions characteristic of HLA-C

The vast majority of new human HLA class I alleles are formed by conversions between existing alleles of the same locus. A notable exception to this rule is HLA-B super(*)4601 formed by replacement of residues 66-76 of the alpha 1 helix of B super(*)1501 by the homologous segment of Cw super(*)0102....

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Veröffentlicht in:The Journal of experimental medicine 1996-08, Vol.184 (2), p.735-740
Hauptverfasser: Barber, L D, Percival, L, Valiante, N M, Chen, L, Lee, C, Gumperz, JE, Phillips, J H, Lanier, L L, Bigge, JC, Parekh, R B, Parham, P
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Sprache:eng
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