Synthesis of the Polycation Thymidyl DNG, Its Fidelity in Binding Polyanionic DNA/RNA, and the Stability and Nature of the Hybrid Complexes

Putative drugs consisting of oligonucleotide analogs capable of combining with RNA or DNA, thereby arresting cellular processes at the translational or transcriptional level, are known as antisense and antigene agents. The backbones of viable antisense/antigene agents do not incorporate phosphodiest...

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Veröffentlicht in:	Journal of the American Chemical Society 1995-06, Vol.117 (22), p.6140-6141
Hauptverfasser:	Dempcy, Robert O, Browne, Kenneth A, Bruice, Thomas C
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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