The mating-specific G sub( alpha ) protein of Saccharomyces cerevisiae downregulates the mating signal by a mechanism that is dependent on pheromone and independent of G sub( beta gamma ) sequestration

It has been inferred from compelling genetic evidence that the pheromone-responsive G sub( alpha ) protein of Saccharomyces cerevisiae, Gpa1, directly inhibits the mating signal by binding to its own beta gamma subunit. Gpa1 has also been implicated in a distinct but as yet uncharacterized negative...

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Veröffentlicht in:Molecular and cellular biology 1996-11, Vol.16 (11), p.6325-6337
Hauptverfasser: Stratton, H F, Zhou, Jianlong, Reed, SI, Stone, DE
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Sprache:eng
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