Double-Strand Cleavage of DNA by a Monofunctional Transition Metal Cleavage Agent

A copper-based transition metal complex has been designed which performs double-stranded cleavage of DNA in a nonrandom fashion. The complex, ((2S,8R)-5-amino-2,8-dibenzyl-5-methyl-3,7-diazanonanedioate)copper(II), presents an ammonium group on one side of the metal equatorial coordination plane to...

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Veröffentlicht in:	Journal of the American Chemical Society 1996-06, Vol.118 (23), p.5339-5345
Hauptverfasser:	Pamatong, Filomena V, Detmer, Charles A, Bocarsly, Jeffrey R
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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